Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262545 | 0.82 | TAS1R3 (0.47) | MEN1KMT2AMAOAMAOBCYP3A4 | |
| SCHEMBL4071188 | 0.80 | ALDH1A1 (0.50) | NPSR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL8809424 | 0.79 | POLB (0.49) | POLBCYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL3826640 | 0.79 | LMNA (0.45) | POLBCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL1010865 | 0.79 | POLB (0.52) | POLBADRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8333706 | 0.79 | POLB (0.52) | POLBCYP1A2CYP2C9CYP2C19L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5266256 | 0.78 | ALDH1A1 (0.45) | POLBCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL8823940 | 0.77 | TARS1 (0.48) | PPARGPPARAMAOA | |
| SCHEMBL4073841 | 0.77 | SMN1; SMN2 (0.49) | CYP1A2CYP2C19SLC6A2SLC6A3GAA | |
| SCHEMBL11682775 | 0.75 | POLB (0.49) | POLBCYP1A2CYP2C9CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063699-A1 | N-ARYLOXYPROPANOLYL-N’-PHENETHYL-UREA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |