Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Pentetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.48 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.48 |
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentetic Acid SCHEMBL7742000 | 1.00 | KDM4E (0.67) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL3821770 | 0.97 | KDM4E (0.62) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Pentetic Acid SCHEMBL9817103 | 0.97 | KDM4E (0.70) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL8606974 | 0.97 | KDM4E (0.62) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL8625956 | 0.97 | KDM4E (0.62) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Pentetic Acid SCHEMBL29678762 | 0.97 | KDM4E (0.70) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Pentetic Acid SCHEMBL275096 | 0.97 | KDM4E (0.70) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL9509467 | 0.97 | KDM4E (0.62) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Pentetic Acid SCHEMBL6230954 | 0.95 | KDM4E (0.67) | KDM4EALOX15MAPTSMN1; SMN2TDP1 | |
| Edetic Acid SCHEMBL10590896 | 0.95 | KDM4E (0.60) | KDM4EALOX15MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589372-A1 | SILVER HALIDE EMULSION, SILVER HALIDE PHOTOGRAPHIC SENSITIVE MATERIAL, AND METHOD OF IMAGE FORMATION | KONICA CORPORATION (JP) | 2005-10-26 | — | — | EP | disclosed |
| EP-0926550-B1 | Image information recording method | KONISHIROKU PHOTO IND (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6376161-B1 | Reading out the image formation while the light-sensitive material is wetted (drying omitted); processing simplified and time shortened to achieve a high quality image and inhibition of unevenness of image and precipitation of salts; scanning | KONICA CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1098221-A2 | Image forming method | KONICA CORPORATION (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0880058-B1 | Method for producing a silver halide photographic light-sensitive material | KONISHIROKU PHOTO IND (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-1048976-A2 | Silver halide color photographic light sensitive material and image forming method by use thereof | KONICA CORPORATION (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-0814375-B1 | Image forming method | KONISHIROKU PHOTO IND (JP) | 1999-12-08 | — | — | EP | disclosed |
| EP-0926550-A1 | Image information recording method | KONICA CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0880058-A1 | Method for producing a silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1998-11-25 | — | — | EP | disclosed |
| US-5837430-A | LIGHT EXPOSURE A SILVER HALIDE EMULSION ON A SUPPORTS, AMPLIFYING DEVELOPMENT WITH A LOW CONCENTRATION SILVER CHLORIDE CONTENT IN EACH YELLOW, MAGENTA AND CYAN IMAGE FORMING LAYERS | KONICA CORPORATION (JP) | 1998-11-17 | — | — | US | disclosed |
| EP-0549175-B1 | Method of forming a color image | KONISHIROKU PHOTO IND (JP) | 1998-04-22 | — | — | EP | disclosed |
| EP-0814375-A1 | Image forming method | KONICA CORPORATION (JP) | 1997-12-29 | — | — | EP | disclosed |
| EP-0768570-A1 | Image forming method | KONICA CORPORATION (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0671656-A2 | Silver halide light-sensitive color photographic material and method of preparing color proof | KONICA CORPORATION (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0589694-A1 | Silver halide light-sensitive photographic material | KONICA CORPORATION (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0549175-A1 | Method of forming a color image | KONICA CORPORATION (JP) | 1993-06-30 | — | — | EP | disclosed |