Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604190 | 0.79 | ATM (0.40) | ALDH1A1ACHE | |
| SCHEMBL604250 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL16026989 | 0.64 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL604834 | 0.63 | ATM (0.39) | ALDH1A1ACHE | |
| SCHEMBL17399094 | 0.63 | TRPV1 (0.43) | — | |
| SCHEMBL12474022 | 0.60 | SLC6A9 (0.39) | — | |
| SCHEMBL13737184 | 0.60 | ADRB2 (0.52) | — | |
| SCHEMBL28057481 | 0.58 | BCHE (0.50) | BCHEALDH1A1 | |
| SCHEMBL24209706 | 0.56 | ARG1 (0.37) | — | |
| SCHEMBL15729339 | 0.56 | EPHX2 (0.47) | KLKB1ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603481-A2 | AMINOINDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | Abbott GmbH & Co. KG (DE) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020131-A2 | AMINOINDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2012-02-16 | — | — | WO | disclosed |