Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.36 |
| ▸ | CA2 | P00918 | 8/20 | 0.36 |
| ▸ | CA9 | Q16790 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2519902 | 1.00 | DNM1 (0.39) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL2301357 | 0.91 | LPAR2 (0.44) | — | |
| SCHEMBL935452 | 0.82 | ALDH1A1 (0.41) | — | |
| SCHEMBL12257499 | 0.78 | LPAR3 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL12257497 | 0.78 | LPAR3 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11508110 | 0.76 | THRB (0.38) | CA1CA2CA9CA12CA7 | |
| SCHEMBL15554489 | 0.76 | THRB (0.38) | CA1CA2CA9CA12CA7 | |
| SCHEMBL6021113 | 0.74 | MEN1 (0.45) | TSHRCES2THRBMEN1HTT | |
| SCHEMBL14118722 | 0.74 | DNM1 (0.42) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL1254027 | 0.74 | DNM1 (0.42) | DNM1CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558562-A1 | CATIONIC CARDIOLIPIN ANALOGS AND USE THEREOF | Neopharm, Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004035523-A1 | CATIONIC CARDIOLIPIN ANALOGS AND USE THEREOF | NEOPHARM, INC. (US) | 2004-04-29 | — | — | WO | disclosed |