Diprobutine

Diprobutine

SCHEMBL626403

CCCC(N)(CCC)CCC.COP(=O)(O)OC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 11/20 0.50
SMPD1 P17405 5/20 0.40
GRM4 Q14833 1/20 0.35
GGPS1 O95749 4/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241994 0.88 FDPS (0.53) FDPSSMPD1GGPS1
SCHEMBL625998 0.86 FDPS (0.55) FDPSSMPD1GGPS1
SCHEMBL626715 0.84 FDPS (0.56) FDPSSMPD1GGPS1
SCHEMBL10788763 0.82 FDPS (0.38) FDPSSMPD1GRM4S1PR1S1PR3
Propane SCHEMBL4629637 0.75 CA2 (0.35) FDPS
Diethyl Hydrogen Phosphate SCHEMBL625440 0.75 FDPS (0.48) FDPSSMPD1GGPS1S1PR1S1PR3
Alcohol SCHEMBL7622017 0.73 PPARD (0.39) FDPS
Methylamine SCHEMBL28070982 0.72
SCHEMBL29265510 0.72 FDPS (0.40) FDPSSMPD1GGPS1
Diprobutine SCHEMBL219202 0.72 FDPS (0.41) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871924-B2 Regioselectively substituted cellulose esters produced in a tetraalkylammonium alkylphosphate ionic liquid process and products produced therefrom EASTMAN CHEMICAL COMPANY (US) 2014-10-28 US claimed
US-8524887-B2 Regioselectively substituted cellulose esters produced in a tetraalkylammonium alkylphosphate ionic liquid process and products produced therefrom EASTMAN CHEMICAL COMPANY (US) 2013-09-03 US claimed
US-20120121830-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS PRODUCED IN A TETRAALKYLAMMONIUM ALKYLPHOSPHATE IONIC LIQUID PROCESS AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2012-05-17 US claimed
EP-2419454-A1 CELLULOSE SOLUTIONS COMPRISING TETRAALKYLAMMONIUM ALKYLPHOSPHATE AND PRODUCTS PRODUCED THEREFROM Eastman Chemical Company (US) 2012-02-22 EP claimed
US-20120041080-A1 CELLULOSE SOLUTIONS COMPRISING TETRAALKYLAMMONIUM ALKYLPHOSPHATE AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2012-02-16 US claimed
US-8067488-B2 Cellulose solutions comprising tetraalkylammonium alkylphosphate and products produced therefrom EASTMAN CHEMICAL COMPANY (US) 2011-11-29 US claimed
US-20100305249-A1 CELLULOSE SOLUTIONS COMPRISING TETRAALKYLAMMONIUM ALKYLPHOSPHATE AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2010-12-02 US claimed
WO-2010120269-A1 CELLULOSE SOLUTIONS COMPRISING TETRAALKYLAMMONIUM ALKYLPHOSPHATE AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2010-10-21 WO claimed
US-9926384-B2 Regioselectively substituted cellulose esters produced in a tetraalkylammonium alkylphosphate ionic liquid process and products produced therefrom EASTMAN CHEMICAL COMPANY (US) 2018-03-27 US disclosed
EP-3216806-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS PRODUCED IN A TETRAALKYLAMMONIUM ALKYLPHOSPHATE IONIC LIQUID PROCESS AND PRODUCTS PRODUCED THEREFROM Eastman Chemical Company (US) 2017-09-13 EP disclosed
US-8901054-B2 Cellulose and cellulose ether solutions and use thereof SE TYLOSE GMBH & CO., KG (DE) 2014-12-02 US disclosed
US-20140343271-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS PRODUCED IN A TETRAALKYLAMMONIUM ALKYLPHOSPHATE IONIC LIQUID PROCESS AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2014-11-20 US disclosed
US-8871924-B2 Regioselectively substituted cellulose esters produced in a tetraalkylammonium alkylphosphate ionic liquid process and products produced therefrom EASTMAN CHEMICAL COMPANY (US) 2014-10-28 US disclosed
US-20140171352-A1 CELLULOSE AND CELLULOSE ETHER SOLUTIONS AND USE THEREOF SE TYLOSE GMBH & CO. KG (DE) 2014-06-19 US disclosed
US-20120041080-A1 CELLULOSE SOLUTIONS COMPRISING TETRAALKYLAMMONIUM ALKYLPHOSPHATE AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2012-02-16 US disclosed
US-8067488-B2 Cellulose solutions comprising tetraalkylammonium alkylphosphate and products produced therefrom EASTMAN CHEMICAL COMPANY (US) 2011-11-29 US disclosed
US-20100305249-A1 CELLULOSE SOLUTIONS COMPRISING TETRAALKYLAMMONIUM ALKYLPHOSPHATE AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2010-12-02 US disclosed
WO-2010120269-A1 CELLULOSE SOLUTIONS COMPRISING TETRAALKYLAMMONIUM ALKYLPHOSPHATE AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2010-10-21 WO disclosed
WO-2010120268-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS PRODUCED IN A TETRAALKYLAMMONIUM ALKYLPHOSPHATE IONIC LIQUID PROCESS AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2010-10-21 WO disclosed
US-20100267942-A1 REGIOSELECTIVELY SUBSTITUTED CELLULOSE ESTERS PRODUCED IN A TETRAALKYLAMMONIUM ALKYLPHOSPHATE IONIC LIQUID PROCESS AND PRODUCTS PRODUCED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041080-A1 CELLULOSE SOLUTIONS COMPRISING TETRAALKYLAMMONIUM ALKYLPHOSPHATE AND PRODUCTS PRODUCED THEREFROM AGPS, THEM6, PCTP FDPS 1618/4885SMPD1 771/4885GRM4 4603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.