Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18393481 | 0.85 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL907264 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TSHRTHRBCYP2D6CYP2C19 | |
| SCHEMBL17636413 | 0.82 | THRB (0.43) | ALDH1A1TSHRTHRBCYP2D6CYP2C19 | |
| SCHEMBL23894805 | 0.81 | THRB (0.48) | ALDH1A1TSHRTHRBCYP2D6CYP2C19 | |
| SCHEMBL6263428 | 0.80 | — | — | |
| SCHEMBL12297123 | 0.79 | THRB (0.47) | ALDH1A1TSHRTHRBCYP2D6CYP2C19 | |
| Phosphonic Acid SCHEMBL17455418 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TSHRTHRB | |
| SCHEMBL16654664 | 0.78 | THRB (0.55) | ALDH1A1TSHRTHRBCYP2D6CYP2C19 | |
| SCHEMBL15382568 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRBCYP2D6CYP2C19 | |
| Phosphoric Acid SCHEMBL5595983 | 0.78 | THRB (0.47) | ALDH1A1TSHRTHRBCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3120827-B1 | ADHESIVE DENTAL MATERIALS WITH STRONGLY ACIDIC ADHESIVE POLYMERS | IVOCLAR VIVADENT AG (LI) | 2019-02-06 | — | — | EP | claimed |
| US-9833389-B2 | Adhesive dental materials with strongly acidic adhesive polymers | IVOCLAR VIVADENT AG (LI) | 2017-12-05 | — | — | US | claimed |
| EP-3120827-B1 | ADHESIVE DENTAL MATERIALS WITH STRONGLY ACIDIC ADHESIVE POLYMERS | IVOCLAR VIVADENT AG (LI) | 2019-02-06 | — | — | EP | disclosed |
| US-9833389-B2 | Adhesive dental materials with strongly acidic adhesive polymers | IVOCLAR VIVADENT AG (LI) | 2017-12-05 | — | — | US | disclosed |
| US-9833389-B2 | Adhesive dental materials with strongly acidic adhesive polymers | IVOCLAR VIVADENT AG (LI) | 2017-12-05 | — | — | US | disclosed |
| US-9833389-B2 | Adhesive dental materials with strongly acidic adhesive polymers | IVOCLAR VIVADENT AG (LI) | 2017-12-05 | — | — | US | disclosed |
| US-20170020791-A1 | ADHESIVE DENTAL MATERIALS WITH STRONGLY ACIDIC ADHESIVE POLYMERS | IVOCLAR VIVADENT AG (US) | 2017-01-26 | — | — | US | disclosed |
| US-20170020791-A1 | ADHESIVE DENTAL MATERIALS WITH STRONGLY ACIDIC ADHESIVE POLYMERS | IVOCLAR VIVADENT AG (US) | 2017-01-26 | — | — | US | disclosed |
| US-20170020791-A1 | ADHESIVE DENTAL MATERIALS WITH STRONGLY ACIDIC ADHESIVE POLYMERS | IVOCLAR VIVADENT AG (US) | 2017-01-26 | — | — | US | disclosed |
| EP-3120827-A1 | ADHESIVE DENTAL MATERIALS WITH STRONGLY ACIDIC ADHESIVE POLYMERS | Ivoclar Vivadent AG (LI) | 2017-01-25 | — | — | EP | disclosed |
| EP-1374829-B1 | Dental material on the basis of acryloester phosphonic acid | IVOCLAR VIVADENT AG (LI) | 2005-11-02 | — | — | EP | disclosed |
| US-20040077754-A1 | Dental materials based on acrylic-ester phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2004-04-22 | — | — | US | disclosed |
| US-6710149-B2 | USE OF ACRYLOPHOSPHONIC ACID AS A COMPONENT OF AN ADHESIVE, OF A POLYMER, OF A COMPOSITE, OF A CEMENT, OF A MOLDED ARTICLE AND IN PARTICULAR OF A DENTAL MATERIAL | IVOCLAR VIVADENT AG (LI) | 2004-03-23 | — | — | US | disclosed |
| EP-1374829-A1 | Dental material on the basis of acryloester phosphonic acid | Ivoclar Vivadent AG (LI) | 2004-01-02 | — | — | EP | disclosed |
| EP-1148060-B1 | Hydrolysis-stable and polymerisable acrylphosphonic acids | IVOCLAR VIVADENT AG (LI) | 2003-09-10 | — | — | EP | disclosed |
| US-6350839-B2 | THE MONOESTER OF THE PHOSPHONIC ACID GROUP ALSO HAS IMPROVED SOLUBILITY IN POLAR ORGANIC SOLVENTS, AND WATER THAN THE CORRESPONDING ACID; USE IN DENTISTRY | IVOCLAR VIVADENT AG (LI) | 2002-02-26 | — | — | US | disclosed |
| US-20020016384-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid | IVOCLAR VIVADENT AG. | 2002-02-07 | — | — | US | disclosed |
| US-20010044513-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid monoesters | IVOCLAR VIVADENT AG | 2001-11-22 | — | — | US | disclosed |
| EP-1148071-A2 | Hydrolysis-stable and polymerisable acrylphosphonic acid mono esters | Ivoclar Vivadent AG (LI) | 2001-10-24 | — | — | EP | disclosed |
| EP-1148060-A1 | Hydrolysis-stable and polymerisable acrylphosphonic acids | Ivoclar Vivadent AG (LI) | 2001-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077754-A1 | Dental materials based on acrylic-ester phosphonic acids | PHOSPHO1, RER1, PTGER1 | ALDH1A1 804/4885TSHR 3383/4885THRB 2845/4885 |
| US-20020016384-A1 | Hydrolysis-stable and polymerizable acrylophosphonic acid | PHOSPHO1, PPA1, ABHD16A | ALDH1A1 374/4885TSHR 3483/4885THRB 3690/4885 |
| US-20170020791-A1 | ADHESIVE DENTAL MATERIALS WITH STRONGLY ACIDIC ADHESIVE POLYMERS | ITGA1, EPCAM, ITGAM | ALDH1A1 850/4885TSHR 4502/4885THRB 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.