Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047633 | 0.81 | RECQL (0.41) | HTTMEN1KMT2AIDO1ALDH1A1 | |
| SCHEMBL5049925 | 0.81 | RECQL (0.41) | HTTMEN1KMT2AIDO1ALDH1A1 | |
| SCHEMBL5322587 | 0.81 | RECQL (0.41) | HTTMEN1KMT2AIDO1ALDH1A1 | |
| SCHEMBL3984863 | 0.77 | KDM4E (0.42) | MAPTPOLBHTTMEN1KMT2A | |
| SCHEMBL5907397 | 0.76 | GABRA1 (0.44) | PTPRCMAPTPOLBHTTMEN1 | |
| SCHEMBL11518803 | 0.74 | GPR35 (0.53) | PTPRCMAPTPOLBHTTMEN1 | |
| SCHEMBL29573133 | 0.74 | GPR35 (0.53) | PTPRCMAPTPOLBHTTMEN1 | |
| SCHEMBL28923513 | 0.74 | PTPRC (0.46) | PTPRCMAPTPOLBHTTMEN1 | |
| SCHEMBL3398674 | 0.74 | SLC6A3 (0.44) | PTPRCMAPTHTTMEN1KMT2A | |
| SCHEMBL2011606 | 0.74 | P2RX3 (0.37) | MAPTPOLBHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |