Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132037 | 0.82 | CDK4 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Hydrochloric Acid SCHEMBL17669542 | 0.77 | IMPDH2 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3874834 | 0.77 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1026408 | 0.77 | MAPT (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3874790 | 0.74 | IMPDH2 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1635466 | 0.73 | ALDH1A1 (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29380761 | 0.73 | ALDH1A1 (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1260958 | 0.73 | HTT (0.51) | HTTKIF11ALDH1A1GPR3HSD17B10 | |
| SCHEMBL3433644 | 0.72 | IMPDH2 (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30678031 | 0.72 | IMPDH2 (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598418-A1 | STABILISED COMPOSITION FOR FLUORIMETRIC, COLORIMETRIC OR CHEMOLUMINESCENT ASSAYS, KITS CONTAINING SAME AND PRODUCTION METHOD THEREOF | BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. (ES) | 2005-11-23 | — | — | EP | disclosed |
| WO-2002018544-A9 | METHOD AND REAGENTS FOR TREATMENT OF SKIN DISORDERS BY MODULATING THE NOTCH PATHWAY | UNIV LOYOLA CHICAGO (US) | 2003-04-03 | — | — | WO | disclosed |
| US-20020151487-A1 | Method and reagents for epithelial barrier formation and treatment of malignant and benign skin disorders by modulating the notch pathway | LOYOLA UNIVERSITY CHICAGO | 2002-10-17 | — | — | US | disclosed |
| WO-2002018544-A2 | METHOD AND REAGENTS FOR TREATMENT OF SKIN DISORDERS BY MODULATING THE NOTCH PATHWAY | LOYOLA UNIVERSITY CHICAGO (US) | 2002-03-07 | — | — | WO | disclosed |
| US-RE37187-E1 | SOYBEAN EXTRACT | AJINOMOTO CO., INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0794253-B1 | Aminopeptidase GX, and a method of hydrolyzing a protein with the same | AJINOMOTO KK (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5824534-A | ENZYMES FOR HYDROLYZING PEPTIDES AND PROTEINS | AJINOMOTO CO., INC. (JP) | 1998-10-20 | — | — | US | disclosed |
| US-5707624-A | ADMINISTERING ANTIBODIES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-01-13 | — | — | US | disclosed |
| CN-1166526-A | Aminopeptidase GX, and method of hydrolyzing protein with the same | AJINOMOTO KK (JP) | 1997-12-03 | — | — | CN | disclosed |
| EP-0794253-A2 | Aminopeptidase GX, and a method of hydrolyzing a protein with the same | Ajinomoto Co., Ltd. (JP) | 1997-09-10 | — | — | EP | disclosed |