SCHEMBL1026408

SCHEMBL1026408

CCc1c(N)ccc2c1[nH]c1ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
MAPK1 P28482 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
KIF11 P52732 7/20 0.47
GABRP O00591 2/20 0.46
GABRD O14764 2/20 0.46
GABRA1 P14867 2/20 0.46
GABRB1 P18505 2/20 0.46
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
GABRA5 P31644 2/20 0.46
GABRA3 P34903 2/20 0.46
GABRA2 P47869 2/20 0.46
GABRB2 P47870 2/20 0.46
GABRA4 P48169 2/20 0.46
GABRE P78334 2/20 0.46
GABRA6 Q16445 2/20 0.46
GABRG1 Q8N1C3 2/20 0.46
GABRG3 Q99928 2/20 0.46
GABRQ Q9UN88 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8026806 0.83 KDM4E (0.50) MAPTMAPK1NPSR1KIF11GABRP
SCHEMBL4892845 0.82 PARP1 (0.44) MAPTMAPK1NPSR1KIF11ALDH1A1
SCHEMBL9514812 0.81 MAPT (0.53) MAPTMAPK1NPSR1KIF11GABRP
SCHEMBL9653404 0.80 KIF11 (0.47) MAPTMAPK1NPSR1KIF11GABRP
SCHEMBL3462093 0.79 KIF11 (0.53) MAPTMAPK1NPSR1KIF11GABRP
SCHEMBL28041995 0.77 MAPT (0.59) MAPTMAPK1NPSR1KIF11GABRP
SCHEMBL67665 0.77 KIF11 (0.55) MAPTMAPK1NPSR1KIF11GABRP
SCHEMBL6265148 0.77 GABRP (0.46) MAPTKIF11GABRPGABRDGABRA1
SCHEMBL9644913 0.77 MAPT (0.55) MAPTMAPK1NPSR1KIF11GABRP
SCHEMBL2139000 0.76 KIF11 (0.44) MAPTMAPK1NPSR1KIF11GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090282902-A1 BIO SURFACE ACOUSTIC WAVE (SAW) RESONATOR AMPLIFICATION FOR DETECTION OF A TARGET ANALYTE ATONOMICS A/S (DK) 2009-11-19 US claimed
US-20090191573-A1 METHOD AND KIT FOR DETERMINING ANTIGEN CONTENT IN A SAMPLE USING DOUBLE IMMUNOHISTOCHEMICAL DETECTION UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2009-07-30 US claimed
EP-2059814-A1 METHOD AND KIT FOR DETERMINING ANTIGEN CONTENT IN A SAMPLE USING DOUBLE IMMUNOHISTOCHEMICAL DETECTION UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2009-05-20 EP claimed
EP-2057461-A2 BIO SURFACE ACOUSTIC WAVE (SAW) RESONATOR AMPLIFICATION FOR DETECTION OF A TARGET ANALYTE Atonomics A/S (DK) 2009-05-13 EP claimed
WO-2008023055-A1 METHOD AND KIT FOR DETERMINING ANTIGEN CONTENT IN A SAMPLE USING DOUBLE IMMUNOHISTOCHEMICAL DETECTION UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) 2008-02-28 WO claimed
WO-2008019693-A2 BIO SURFACE ACOUSTIC WAVE (SAW) RESONATOR AMPLIFICATION FOR DETECTION OF A TARGET ANALYTE ATONOMICS A/S (DK) 2008-02-21 WO claimed
EP-1023604-A4 METHOD FOR LOCALIZATION AND QUANTITATION OF A SUBSTANCE IN A BIOLOGICAL SAMPLE UNIV WASHINGTON (US) 2001-05-30 EP claimed
EP-1023604-A1 METHOD FOR LOCALIZATION AND QUANTITATION OF A SUBSTANCE IN A BIOLOGICAL SAMPLE WASHINGTON UNIVERSITY (US) 2000-08-02 EP claimed
US-5902727-A SIMPLE AND EFFICIENT ANALYSIS BY BINDING ENZYME LINKED PROBE TO TARGET, ADDING SUBSTRATE(S), DETECTING INSOLUBLE AND SOLUBLE PRODUCTS WASHINGTON UNIVERSITY (US) 1999-05-11 US claimed
WO-1998010290-A1 METHOD FOR LOCALIZATION AND QUANTITATION OF A SUBSTANCE IN A BIOLOGICAL SAMPLE WASHINGTON UNIVERSITY (US) 1998-03-12 WO claimed
US-20260109783-A1 ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE MESOBLAST, INC. (US) 2026-04-23 US disclosed
US-12589150-B2 Antibodies binding AXL GENMAB A/S (DK) 2026-03-31 US disclosed
US-20260051055-A1 DOMAIN SWAP AND ARTIFICIAL GENERATED VIRTUAL IMAGES VENTANA MEDICAL SYSTEMS, INC. (US) 2026-02-19 US disclosed
US-12275801-B2 Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase MESOBLAST, INC. (US) 2025-04-15 US disclosed
EP-3402822-B1 AXL-SPECIFIC ANTIBODY-DRUG CONJUGATES FOR CANCER TREATMENT GENMAB AS (DK) 2025-03-12 EP disclosed
EP-0197974-A1 ACINO-FOETAL DIFFERENTIATION PROTEINS ASSOCIATED TO THE PANCREAS CANCER, ANTISERUM AND MONOCLONAL ANTIBODIES TO SAID PROTEINS, PREPARATION METHODS Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-10-22 EP disclosed
EP-0196743-A2 Stable chemical compositions containing chromogenic materials and peroxides, and method for obtaining them SAVYON DIAGNOSTICS LTD. (IL) 1986-10-08 EP disclosed
EP-0180496-A1 Acino-foetal differentiation proteins associated with cancer of the pancreas, antiserum and monoclonal antibodies against these proteins and processes for their preparation CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-05-07 EP disclosed
WO-1986002081-A1 ACINO-FOETAL DIFFERENTIATION PROTEINS ASSOCIATED TO THE PANCREAS CANCER, ANTISERUM AND MONOCLONAL ANTIBODIES TO SAID PROTEINS, PREPARATION METHODS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) 1986-04-10 WO disclosed
EP-0118365-A2 Monoclonal antibodies to human breast carcinoma cells and their use in diagnosis and therapy HEALTH RESEARCH, INC. (US) 1984-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589150-B2 Antibodies binding AXL IGSF11, FLT1, VSIG8 MAPT 3294/4885MAPK1 1670/4885NPSR1 486/4885
US-20260109783-A1 ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE ALPP, S100P, ALPG MAPT 2097/4885MAPK1 3337/4885NPSR1 1893/4885
US-20260051055-A1 DOMAIN SWAP AND ARTIFICIAL GENERATED VIRTUAL IMAGES DSG1, DSP, CCND1 MAPT 1007/4885MAPK1 3763/4885NPSR1 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.