Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626697 | 0.82 | CYP11B2 (0.53) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL624950 | 0.77 | MAPT (0.56) | MAPTTHRBRXFP1 | |
| SCHEMBL625664 | 0.76 | MAPT (0.58) | MAPTTHRBRXFP1TP53 | |
| SCHEMBL627767 | 0.72 | L3MBTL1 (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL1944169 | 0.71 | FYN (0.53) | MAPTF2RL3THRBRXFP1CA12 | |
| SCHEMBL532335 | 0.69 | CA12 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19F2RL3 | |
| SCHEMBL1945185 | 0.69 | FYN (0.58) | MAPTF2RL3THRBCA12CA1 | |
| SCHEMBL1762361 | 0.69 | CYP11B1 (1.00) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1945374 | 0.68 | FYN (0.64) | MAPTF2RL3CA12CA1CA2 | |
| SCHEMBL624431 | 0.68 | FYN (0.48) | MAPTF2RL3THRBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |