Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 18/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NEK2 | P51955 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625664 | 0.91 | MAPT (0.58) | MAPTTHRBRXFP1 | |
| SCHEMBL624949 | 0.82 | FYN (0.55) | NEK2 | |
| SCHEMBL626698 | 0.77 | CYP11B2 (0.52) | MAPTTHRBRXFP1 | |
| SCHEMBL625663 | 0.74 | FYN (0.56) | MAPTTHRB | |
| SCHEMBL1945185 | 0.71 | FYN (0.58) | MAPTTHRB | |
| SCHEMBL1944169 | 0.71 | FYN (0.53) | MAPTTHRBRXFP1 | |
| SCHEMBL626106 | 0.71 | THRB (0.49) | MAPTTHRBRXFP1NEK2 | |
| SCHEMBL624431 | 0.70 | FYN (0.48) | MAPTTHRB | |
| SCHEMBL2253571 | 0.70 | FYN (0.52) | MAPTTHRB | |
| SCHEMBL625465 | 0.70 | FYN (0.52) | MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |