Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2215555 | 0.92 | MAPK14 (0.43) | L3MBTL1PKMADRA1AMAPK14KDM4E | |
| SCHEMBL5766219 | 0.92 | MAPK14 (0.43) | L3MBTL1PKMADRA1AMAPK14KDM4E | |
| SCHEMBL14277958 | 0.85 | PPARA (0.42) | L3MBTL1TDP1 | |
| SCHEMBL7165644 | 0.84 | ALDH1A1 (0.45) | MAPTADRA1AMAPK14KDM4EADRA1B | |
| SCHEMBL22013864 | 0.83 | KDM4E (0.40) | L3MBTL1TDP1MAPK14KDM4EADRA1B | |
| SCHEMBL22013866 | 0.83 | KDM4E (0.40) | L3MBTL1TDP1MAPK14KDM4EADRA1B | |
| SCHEMBL13204672 | 0.82 | PKM (0.51) | MAPTTDP1PKMMAPK14KMT2A | |
| SCHEMBL6267008 | 0.82 | PKM (0.51) | MAPTTDP1PKMMAPK14KMT2A | |
| SCHEMBL7742520 | 0.80 | ITGB3 (0.38) | L3MBTL1MAPTADRA1AMAPK14ADRA1B | |
| SCHEMBL7875746 | 0.80 | L3MBTL1 (0.36) | L3MBTL1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688784-B1 | 3'-Modified oligonucleotide derivatives | SANOFI AVENTIS DEUTSCHLAND (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-6326487-B1 | OLIGONUCLEOTIDES, ANTISENSE AGENTS, VIRICIDES AND GENE EXPRESSION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-12-04 | — | — | US | disclosed |
| US-5696248-A | GENE EXPRESSION INHIBITOR, AS PROBES FOR DETECTING NUCLEIC ACIDS, AS VIRICIDES TREATING VIRAL DISEASE CAUSED BY HTLV, INFLUENZA, HEPATITIS VIRUS, PAPILLOMA VIRUS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0688784-A2 | 3'-Modified oligonucleotide derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-27 | — | — | EP | disclosed |