Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627087 | 0.75 | HASPIN (0.42) | HASPINTHRB | |
| SCHEMBL627055 | 0.68 | MAPT (0.48) | MAPTTHRB | |
| SCHEMBL1650185 | 0.59 | TP53 (0.44) | MAPT | |
| SCHEMBL627245 | 0.57 | F2RL3 (0.50) | — | |
| SCHEMBL32665054 | 0.56 | ALDH1A1 (0.42) | MAPT | |
| SCHEMBL21287507 | 0.55 | PTPN11 (0.60) | — | |
| SCHEMBL24462109 | 0.54 | PTGES (0.50) | MAPTTHRB | |
| SCHEMBL21287759 | 0.54 | PTPN11 (0.59) | — | |
| SCHEMBL20935384 | 0.53 | NCF1 (0.41) | — | |
| SCHEMBL14033223 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |