Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490282 | 0.80 | TP53 (0.44) | ALDH1A1MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL6353303 | 0.77 | IDO1 (0.37) | ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL79754 | 0.76 | CALM1 (0.50) | LTA4HALDH1A1 | |
| SCHEMBL7785326 | 0.73 | NQO1 (0.47) | LTA4HALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8939729 | 0.73 | TAAR1 (0.43) | ALDH1A1MAPK1GAARAB9A | |
| SCHEMBL1531987 | 0.73 | IDO1 (0.37) | ALDH1A1MAPK1 | |
| SCHEMBL4390802 | 0.73 | APP (0.37) | — | |
| SCHEMBL8791282 | 0.73 | ESR1 (0.50) | ALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL17956849 | 0.73 | CYP3A4 (0.50) | MAOAALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL1531966 | 0.73 | SIGMAR1 (0.37) | SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450011-A | Compositions and methods for treating metabolic disorders | 阿沃林特有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-1270584-B1 | GLUCOPYRANOSYLOXY BENZYLBENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES FOR THE PREPARATION OF THE DERIVATIVES | KISSEI PHARMACEUTICAL (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-1270584-A1 | GLUCOPYRANOSYLOXY BENZYLBENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES FOR THE PREPARATION OF THE DERIVATIVES | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |