Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503660 | 0.84 | TTR (0.43) | CYP3A4ALDH1A1TDP1TSHRCYP2A6 | |
| SCHEMBL21388680 | 0.84 | ALDH1A1 (0.65) | CYP3A4ALDH1A1TDP1TSHRCYP2A6 | |
| SCHEMBL29502034 | 0.82 | ALDH1A1 (0.50) | CYP3A4ALDH1A1TDP1TSHRCYP2A6 | |
| SCHEMBL178452 | 0.82 | ALDH1A1 (0.50) | CYP3A4ALDH1A1TDP1TSHRCYP2A6 | |
| SCHEMBL1012341 | 0.81 | TDP1 (0.56) | CYP3A4ALDH1A1TDP1TSHRCYP2A6 | |
| SCHEMBL5395473 | 0.81 | TDP1 (0.56) | CYP3A4ALDH1A1TDP1TSHRCYP2A6 | |
| Hydrochloric Acid SCHEMBL6476027 | 0.80 | ALDH1A1 (0.48) | CYP3A4ALDH1A1TDP1TSHRCYP2A6 | |
| SCHEMBL16809161 | 0.79 | ALDH1A1 (0.59) | CYP3A4ALDH1A1TDP1TSHRAR | |
| SCHEMBL352155 | 0.78 | ALDH1A1 (0.50) | CYP3A4ALDH1A1TDP1TSHRCYP2A6 | |
| SCHEMBL1436903 | 0.78 | CYP2A6 (0.52) | ALDH1A1CYP2A6EGLN2ARCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759390-B2 | chemokine receptor 9(CCR9) antagonists such as, 5-Chloro-thiophene-2-sulfonic acid (4-cyano-2-methyl-phenyl)-amide, used for treating autimmune and inflammatory diseases, transplantat rejection and cancer | NOVARTIS AG (CH) | 2010-07-20 | — | — | US | claimed |
| US-20080300295-A1 | Inhibitors of Ccr9 Activity | NOVARTIS AG (CH) | 2008-12-04 | — | — | US | claimed |
| EP-1966182-A1 | INHIBITORS OF CCR9 ACTIVITY | Novartis AG (CH) | 2008-09-10 | — | — | EP | claimed |
| WO-2007071440-A1 | INHIBITORS OF CCR9 ACTIVITY | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | claimed |
| US-12486248-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-02 | — | — | US | disclosed |
| CN-120425579-A | Strong-bundling high-insulation glass fiber cloth and preparation method thereof | 宿迁奕凯新材料科技有限公司 | 2025-08-05 | — | — | CN | disclosed |
| EP-4566596-A1 | ANTI-HBV AGENT | RIKEN (JP) | 2025-06-11 | — | — | EP | disclosed |
| US-20250179072-A1 | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2025-06-05 | — | — | US | disclosed |
| US-20250162992-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-05-22 | — | — | US | disclosed |
| CN-119584960-A | Anti-HBV agents | 国立研究开发法人理化学研究所 | 2025-03-07 | — | — | CN | disclosed |
| CN-119241440-A | Indazole benzoic acid derivative containing urea structure and preparation method and application thereof | 沈阳药科大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-115557907-B | 2,4, 5-Trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-5019493-A | Phenolic cyan coupler and non-color forming sulfonamide; high density; quality | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-05-28 | — | — | US | disclosed |
| US-5006437-A | 2,5-diacylaminophenol coupler, p-dialkylaminoaniline developer noncoloring compound | KONICA CORPORATION (JP) | 1991-04-09 | — | — | US | disclosed |
| US-4882267-A | SULFONAMIDE NON-COLOR-FORMING COMPOUND, HIGH BOILING PHOSPHATE SOLVENT, AMIDO-SUBSTITUTED PHENOLIC CYAN COUPLER | KONICA CORPORATION (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0270341-A2 | Silver halide photographic light-sensitive material with excellent color reproducibility | KONICA CORPORATION (JP) | 1988-06-08 | — | — | EP | disclosed |
| EP-0264083-A2 | Silver halide photographic material and method of forming a dye image thereon | KONICA CORPORATION (JP) | 1988-04-20 | — | — | EP | disclosed |
| EP-0109624-A2 | Process for producing shaped articles made from polyurethane-polyurea which may be cellular | BASF Aktiengesellschaft (DE) | 1984-05-30 | — | — | EP | disclosed |
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300295-A1 | Inhibitors of Ccr9 Activity | CCR9, CCR1, CCR4 | CYP3A4 842/4885ALDH1A1 1383/4885TDP1 1280/4885 |
| US-20250162992-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | NAAA, NCAPH, NCAPD2 | CYP3A4 3087/4885ALDH1A1 1740/4885TDP1 1330/4885 |
| US-20250179072-A1 | TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS | AKR1C2, AKR1B1, AKR1C1 | CYP3A4 141/4885ALDH1A1 234/4885TDP1 1179/4885 |
| US-12486248-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | DHODH, DHPS, DPYD | CYP3A4 325/4885ALDH1A1 132/4885TDP1 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.