Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 6/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625330 | 0.88 | PIM1 (0.52) | FYNPIM1 | |
| SCHEMBL624057 | 0.85 | FYN (0.60) | FYNJAK2JAK3PTK2TGFBR1 | |
| SCHEMBL624434 | 0.83 | JAK2 (0.48) | JAK2JAK3PTK2TGFBR1GPR119 | |
| SCHEMBL627187 | 0.81 | GPR119 (0.44) | GPR119LIMK2 | |
| SCHEMBL623806 | 0.76 | FYN (0.54) | FYNPIM1 | |
| SCHEMBL625243 | 0.76 | FYN (0.60) | FYNJAK2JAK3PTK2 | |
| SCHEMBL628028 | 0.72 | FYN (0.56) | FYNTGFBR1PIM1 | |
| SCHEMBL626982 | 0.72 | FYN (0.56) | FYNGPR119PIM1 | |
| SCHEMBL625331 | 0.71 | PIM1 (0.45) | JAK2JAK3PTK2GPR119MMP13 | |
| SCHEMBL624532 | 0.71 | PIM1 (0.62) | FYNPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |