Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 17/20 | 0.42 |
| ▸ | THRB | P10828 | 17/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1641046 | 0.88 | THRA (0.54) | THRATHRB | |
| SCHEMBL6275008 | 0.83 | THRA (0.59) | THRATHRB | |
| SCHEMBL6273498 | 0.81 | THRB (0.52) | THRATHRB | |
| SCHEMBL6273618 | 0.81 | THRB (0.51) | THRATHRB | |
| SCHEMBL6268739 | 0.80 | THRB (0.54) | THRATHRB | |
| SCHEMBL6275882 | 0.78 | THRA (0.51) | THRATHRB | |
| SCHEMBL6272516 | 0.76 | THRB (0.36) | THRATHRB | |
| SCHEMBL6268718 | 0.75 | THRB (0.46) | THRATHRB | |
| SCHEMBL6271002 | 0.74 | THRB (0.41) | THRATHRB | |
| SCHEMBL1640613 | 0.73 | THRA (0.68) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1297833-B1 | Indole carboxylic acids as thyroid receptor ligands | PFIZER PROD INC (US) | 2005-12-21 | — | — | EP | claimed |