Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376221 | 0.80 | DHFR (0.48) | CTSADHFRHTR2CKDM4EMAPT | |
| SCHEMBL6266844 | 0.77 | CYP2D6 (0.46) | CTSADHFRKDM4EMAPTHPGD | |
| SCHEMBL4533772 | 0.73 | L3MBTL1 (0.62) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL21376419 | 0.73 | RARA (0.57) | HTR2CKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL19832466 | 0.72 | ABL1 (0.46) | CTSAKDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL29375895 | 0.72 | ADORA2A (0.55) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL403698 | 0.72 | ADORA2A (0.55) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL8809704 | 0.71 | CTSA (0.42) | CTSADHFRHTR2CKDM4EMAPT | |
| SCHEMBL6273482 | 0.71 | CTSA (0.44) | CTSADHFRHTR2CKDM4EMAPT | |
| SCHEMBL11839394 | 0.70 | DHFR (0.44) | CTSADHFRKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100301-A1 | 2-ARYLOXYETHYL GLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |