Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL693962 | 0.81 | — | — | |
| SCHEMBL2402405 | 0.81 | — | — | |
| SCHEMBL14992899 | 0.81 | — | — | |
| SCHEMBL11835021 | 0.80 | LMNA (0.36) | LMNAPMP22BLMNPSR1UTS2R | |
| Acrylic Acid SCHEMBL10765500 | 0.79 | ALOX15 (0.30) | — | |
| SCHEMBL2787511 | 0.78 | ACHE (0.37) | TSHR | |
| SCHEMBL6550562 | 0.77 | — | — | |
| SCHEMBL7262843 | 0.76 | DNM1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL7549880 | 0.75 | LCK (0.43) | — | |
| SCHEMBL27690784 | 0.75 | UTS2R (0.31) | LMNAPMP22BLMNPSR1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005117896-A1 | FORMULATIONS CONTAINING FASUDIL, A MATRIX AND AN ENVELOPE | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-12-15 | — | — | WO | disclosed |