Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10083551 | 0.74 | PAX8 (0.52) | RAB9ASMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL625381 | 0.73 | ADORA3 (0.62) | RAB9ASMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL8623427 | 0.73 | EPHX2 (0.59) | SMN1; SMN2KMT2AMEN1TP53MAPT | |
| SCHEMBL27308598 | 0.73 | TP53 (0.54) | RAB9ASMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL16151772 | 0.71 | SMN1; SMN2 (0.69) | RAB9ASMN1; SMN2KMT2ANPC1KDM4E | |
| SCHEMBL625053 | 0.71 | MEN1 (0.58) | RAB9ASMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL18078704 | 0.70 | SMN1; SMN2 (0.73) | RAB9ASMN1; SMN2KMT2ANPC1KDM4E | |
| Hydrochloric Acid SCHEMBL16428996 | 0.69 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL27806626 | 0.69 | LMNA (0.67) | RAB9ASMN1; SMN2KMT2ANPC1MEN1 | |
| SCHEMBL14962259 | 0.69 | KDM4E (0.64) | RAB9ASMN1; SMN2KMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |