Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756730 | 0.87 | FOLH1 (0.49) | ALDH1A1MAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL9756728 | 0.85 | SGMS2 (0.43) | LMNAHPGDALDH1A1HDAC6MAPT | |
| SCHEMBL13662895 | 0.78 | LMNA (0.58) | LMNAHPGDUSP2ALDH1A1TSHR | |
| SCHEMBL4870023 | 0.78 | LMNA (0.52) | LMNAHPGDUSP2ALDH1A1TSHR | |
| SCHEMBL1305662 | 0.78 | HPGD (0.57) | LMNAHPGDUSP2ALDH1A1TSHR | |
| SCHEMBL6274464 | 0.77 | HTR6 (0.46) | LMNAHPGDMAPTFFAR4KMT2A | |
| SCHEMBL2338199 | 0.76 | HPGD (0.76) | LMNAHPGDUSP2ALDH1A1TSHR | |
| SCHEMBL24983669 | 0.76 | LMNA (0.56) | LMNAHPGDUSP2ALDH1A1TSHR | |
| SCHEMBL4307561 | 0.76 | LMNA (0.56) | LMNAHPGDUSP2ALDH1A1TSHR | |
| SCHEMBL30141003 | 0.76 | LMNA (0.56) | LMNAHPGDUSP2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077432-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0438752-A1 | Monobactam hydrazides containing catechol sulfonic acid groups | E.R. SQUIBB & SONS, INC. (US) | 1991-07-31 | — | — | EP | disclosed |
| US-5030724-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-07-09 | — | — | US | disclosed |