SCHEMBL627550

SCHEMBL627550

Cc1ccc2c(c1)Sc1cc(C)ccc1N2C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.52
NOX1 Q9Y5S8 7/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
DRD3 P35462 2/20 0.52
ADRA2A P08913 1/20 0.52
ADRA2B P18089 1/20 0.52
ADRA2C P18825 1/20 0.52
CHRM3 P20309 1/20 0.52
SLC6A2 P23975 1/20 0.52
HTR2C P28335 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR2B P41595 1/20 0.52
SNCA P37840 4/20 0.47
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392464 1.00 MAOA (0.52) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL2756770 0.92 NOX1 (0.50) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL628765 0.90 MAOA (0.70) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL16079009 0.84 MAPT (0.49) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL16075972 0.82 MAPT (0.40) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL11927569 0.82 MAOA (0.52) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL20923558 0.82 NOX1 (0.38) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL2756738 0.82 NOX1 (0.42) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL22779317 0.80 NOX1 (0.37) MAOANOX1MEN1KMT2AL3MBTL1
SCHEMBL25028085 0.79 NOX1 (0.42) MAOANOX1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112631032-B Composition for forming solution-type electrochromic layer, and electrochromic layer and electrochromic device prepared therefrom 青岛凯欧斯光电科技有限公司 2022-12-09 CN claimed
CN-112631033-B Composition for forming solution-type electrochromic layer, and electrochromic layer and electrochromic device prepared therefrom 青岛凯欧斯光电科技有限公司 2022-11-01 CN claimed
US-11414595-B2 Electrochromic compounds and devices GENTEX CORPORATION (US) 2022-08-16 US claimed
EP-4038450-A1 ELECTRO-OPTIC ELEMENTS AND METHOD OF FORMING GENTEX CORPORATION (US) 2022-08-10 EP claimed
CN-114667482-A Electro-optical element and forming method 金泰克斯公司 2022-06-24 CN claimed
EP-3948414-A1 ELECTRO-OPTIC SUB-ASSEMBLIES AND ASSEMBLIES HAVING AN ELECTROCHROMIC GEL LAYER GENTEX CORPORATION (US) 2022-02-09 EP claimed
CN-113614629-A Electro-optical subassembly and assembly with electrochromic gel layer 金泰克斯公司 2021-11-05 CN claimed
US-20210318584-A9 ELECTROCHROMIC COMPOUNDS AND DEVICES GENTEX CORPORATION 2021-10-14 US claimed
CN-112631032-A Composition for forming solution-type electrochromic layer, and electrochromic layer and electrochromic device prepared therefrom 北京开阳亮微科技有限公司 2021-04-09 CN claimed
CN-112631033-A Composition for forming solution-type electrochromic layer, and electrochromic layer and electrochromic device prepared therefrom 北京开阳亮微科技有限公司 2021-04-09 CN claimed
EP-1328842-A1 COLOR-STABILIZED ELECTROCHROMIC DEVICES GENTEX CORPORATION (US) 2003-07-23 EP claimed
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US claimed
US-6433914-B1 Color-stabilized electrochromic devices GENTEX CORPORATION 2002-08-13 US claimed
EP-1204898-A1 COLOR-STABILIZED ELECTROCHROMIC DEVICES Gentex Corporation (US) 2002-05-15 EP claimed
WO-2002019022-A1 COLOR-STABILIZED ELECTROCHROMIC DEVICES GENTEX CORPORATION (US) 2002-03-07 WO claimed
WO-2001013169-A1 COLOR-STABILIZED ELECTROCHROMIC DEVICES GENTEX CORPORATION (US) 2001-02-22 WO claimed
US-6188505-B1 Color-stabilized electrochromic devices GENTEX CORPORATION 2001-02-13 US claimed
JP-2000512267-A 2000-09-19 JP claimed
EP-0912097-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1999-05-06 EP claimed
WO-1997042825-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1997-11-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210318584-A9 ELECTROCHROMIC COMPOUNDS AND DEVICES KCND2, KCNH2, KCNC1 MAOA 262/4885NOX1 915/4885MEN1 3563/4885
US-11414595-B2 Electrochromic compounds and devices KCND2, KCNH2, KCNC1 MAOA 262/4885NOX1 915/4885MEN1 3563/4885
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 MAOA 1245/4885NOX1 261/4885MEN1 4044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.