Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286589 | 0.82 | F2 (0.53) | CYP2D6CYP2C9TSHRCYP2C19F2 | |
| SCHEMBL6280117 | 0.82 | MEN1 (0.60) | CYP2D6CYP2C9TSHRCYP2C19F2 | |
| SCHEMBL7115524 | 0.79 | PRMT1 (0.47) | F2TMPRSS6PRMT1F10SMN1; SMN2 | |
| SCHEMBL6276427 | 0.79 | GPR55 (0.56) | CYP2D6CYP2C9TSHRCYP2C19F2 | |
| SCHEMBL4168948 | 0.75 | KEAP1 (0.61) | CYP2D6CYP2C9TSHRCYP2C19NAMPT | |
| SCHEMBL8170686 | 0.75 | KEAP1 (0.65) | F2TMPRSS6PLAUHPNPRMT1 | |
| SCHEMBL6285904 | 0.74 | NAMPT (0.56) | F2TMPRSS6NAMPTF10SMN1; SMN2 | |
| SCHEMBL6276930 | 0.74 | CA2 (0.53) | TSHRSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL6280114 | 0.70 | NAMPT (0.62) | F2TMPRSS6NAMPTSMN1; SMN2KMT2A | |
| SCHEMBL19639277 | 0.70 | KEAP1 (0.61) | CYP2D6CYP2C9TSHRCYP2C19NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949567-B2 | Compounds for the treatment of protozoal diseases | 4SC AG (DE) | 2005-09-27 | — | — | US | disclosed |
| US-20030119876-A1 | Compounds for the treatment of protozoal diseases | 4SC AG (DE) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119876-A1 | Compounds for the treatment of protozoal diseases | CLIC1, PKD2, PKD1 | CYP2D6 2377/4885CYP2C9 2775/4885TSHR 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.