Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.67 |
| ▸ | FLT4 | P35916 | 3/20 | 0.67 |
| ▸ | KDR | P35968 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319458 | 0.94 | FLT1 (0.58) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL8658489 | 0.86 | FLT1 (0.65) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL7213399 | 0.84 | PTGS2 (0.64) | FLT1FLT4KDRMEN1LMNA | |
| Styrene SCHEMBL8648561 | 0.84 | FLT1 (0.63) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL7209934 | 0.84 | FLT1 (0.79) | FLT1FLT4KDRL3MBTL1PTGS2 | |
| SCHEMBL174010 | 0.84 | FLT1 (0.77) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL29011132 | 0.83 | FLT1 (0.74) | FLT1FLT4KDRMEN1LMNA | |
| Potassium SCHEMBL30358590 | 0.83 | FLT1 (0.74) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL8424044 | 0.81 | FLT1 (0.73) | FLT1FLT4KDRMEN1LMNA | |
| SCHEMBL21162099 | 0.81 | FLT1 (0.63) | FLT1FLT4KDRMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055292-B1 | PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2017-08-16 | — | — | EP | claimed |
| EP-3055292-A1 | PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052156-A1 | PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-04-16 | — | — | WO | disclosed |
| US-6974870-B2 | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHAMACEUTICALS, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| US-20040180922-A1 | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-09-16 | — | — | US | disclosed |
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180922-A1 | Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses | NFKBIA, IKBKB, CHUK | FLT1 2081/4885FLT4 2826/4885KDR 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.