Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 12/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266369 | 0.89 | ADAMTS5 (0.39) | ALDH1A1MAPTKDM4ETDP1GAA | |
| SCHEMBL6278562 | 0.88 | ADAMTS5 (0.35) | ALDH1A1MAPTKDM4ETDP1GAA | |
| SCHEMBL6277544 | 0.86 | KDM4E (0.34) | ALDH1A1MAPTKDM4ETDP1GAA | |
| SCHEMBL6278050 | 0.85 | SIRT1 (0.38) | ALDH1A1MAPTKDM4ETDP1GAA | |
| SCHEMBL6277489 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ETDP1GAA | |
| SCHEMBL6274203 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4ETDP1GAA | |
| SCHEMBL6262704 | 0.77 | ADAMTS5 (0.49) | ALDH1A1MAPTKDM4ETDP1GAA | |
| SCHEMBL6262688 | 0.76 | KMT2A (0.36) | ALDH1A1MAPTKDM4EL3MBTL1HPGD | |
| SCHEMBL6274808 | 0.76 | ADAMTS5 (0.41) | ALDH1A1MAPTKDM4ETDP1GAA | |
| SCHEMBL6274347 | 0.74 | ADAMTS5 (0.47) | ALDH1A1MAPTKDM4ETDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | disclosed |