Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266369 | 0.85 | ADAMTS5 (0.39) | ADAMTS5NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL6277544 | 0.80 | KDM4E (0.34) | NPC1RAB9AMAPTL3MBTL1KDM4E | |
| SCHEMBL6278562 | 0.79 | ADAMTS5 (0.35) | ADAMTS5NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL6262688 | 0.73 | KMT2A (0.36) | NPC1RAB9AMAPTL3MBTL1POLB | |
| SCHEMBL6274449 | 0.65 | RAB9A (0.33) | SIRT1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL6274347 | 0.63 | ADAMTS5 (0.47) | ADAMTS5NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL6274203 | 0.62 | ALDH1A1 (0.49) | ADAMTS5NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL11064449 | 0.62 | PRMT6 (0.54) | SIRT1NPC1RAB9AAPOBEC3GMAPT | |
| SCHEMBL6274201 | 0.60 | ADAMTS5 (0.37) | ADAMTS5MAPTRECQLKDM4EALDH1A1 | |
| SCHEMBL6260436 | 0.58 | MECP2 (0.47) | ADAMTS5NPC1RAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | disclosed |