SCHEMBL6277239

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17501637	0.91	MAPT (0.50)	L3MBTL1APLNRALDH1A1MAPTMTNR1A
	SCHEMBL24041775	0.84	APLNR (0.50)	APLNRALDH1A1SMN1; SMN2LMNATSHR
	SCHEMBL11445546	0.83	CYP1A2 (0.50)	L3MBTL1ALDH1A1SMN1; SMN2TSHRNPC1
	SCHEMBL9451340	0.83	CA1 (0.55)	L3MBTL1ALDH1A1MAPTMTNR1AMTNR1B
	SCHEMBL6271706	0.83	MEN1 (0.46)	L3MBTL1ALDH1A1MAPTLMNAKMT2A
	SCHEMBL4469836	0.83	APP (0.42)	ALDH1A1MAPTLMNATSHRNPC1
	SCHEMBL3947128	0.83	LTA4H (0.50)	L3MBTL1ALDH1A1MAPTPKMKMT2A
	SCHEMBL16964735	0.83	CA12 (0.47)	ALDH1A1LMNATSHRHTTKMT2A
	SCHEMBL1751861	0.83	KDM4E (0.45)	ALDH1A1MAPTSMN1; SMN2LMNATSHR
	SCHEMBL7976554	0.82	KCNA3 (0.52)	L3MBTL1ALDH1A1MAPTMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.