Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281696 | 0.85 | HTR2C (0.46) | HTR2CNPSR1TSHRKDM4ELMNA | |
| SCHEMBL6286208 | 0.83 | HTT (0.42) | HTR2CNPSR1TSHRKDM4ELMNA | |
| SCHEMBL29560191 | 0.77 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2PREP | |
| SCHEMBL30781570 | 0.76 | POLB (0.44) | HTR2CNPC1RAB9ASMN1; SMN2AGTR2 | |
| SCHEMBL6475389 | 0.76 | PREP (0.49) | NPSR1TSHRKDM4ELMNAHSD17B10 | |
| SCHEMBL6475398 | 0.76 | PREP (0.49) | NPSR1TSHRKDM4ELMNAHSD17B10 | |
| SCHEMBL6484219 | 0.76 | PREP (0.49) | NPSR1TSHRKDM4ELMNAHSD17B10 | |
| SCHEMBL31390598 | 0.75 | CTSL (0.41) | HTR2CHPGDFKBP1ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2727664 | 0.75 | SMN1; SMN2 (0.41) | HTR2CNPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2843333 | 0.75 | SMN1; SMN2 (0.41) | HTR2CNPSR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900238-B1 | HIV protease inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-05-31 | — | — | US | disclosed |
| WO-1997021100-A9 | HIV PROTEASE INHIBITORS | — | 1997-10-30 | — | — | WO | disclosed |