Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2843333 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL30694003 | 0.83 | PSEN1 (0.40) | — | |
| SCHEMBL29185150 | 0.83 | PSEN1 (0.40) | — | |
| SCHEMBL29560191 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2C19NPC1RAB9A | |
| SCHEMBL30693995 | 0.81 | AGTR2 (0.40) | SMN1; SMN2NPC1RAB9AHTR2C | |
| SCHEMBL3742158 | 0.80 | DUT (0.34) | — | |
| SCHEMBL211191 | 0.80 | DUT (0.34) | — | |
| SCHEMBL6475389 | 0.80 | PREP (0.49) | NPSR1 | |
| SCHEMBL6475398 | 0.80 | PREP (0.49) | NPSR1 | |
| SCHEMBL6484219 | 0.80 | PREP (0.49) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522593-B2 | Azacycloalkyl carbonyl cyclic amine compound | ALIVEXIS, INC. (JP) | 2026-01-13 | — | — | US | disclosed |
| US-20250163041-A1 | AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND | ALIVEXIS, INC. (JP) | 2025-05-22 | — | — | US | disclosed |
| EP-4538264-A1 | AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND | Alivexis, Inc. (JP) | 2025-04-16 | — | — | EP | disclosed |
| CN-119317620-A | Azacycloalkyl carbonyl cyclic amine compounds | 亚力维克希斯股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2023243601-A1 | AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND | モジュラス株式会社 | 2023-12-21 | — | — | WO | disclosed |
| US-8895582-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8759374-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8759374-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2013-02-28 | — | — | US | disclosed |
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2013-02-28 | — | — | US | disclosed |
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | SMN1; SMN2 252/4885CYP2C19 2307/4885NPC1 4684/4885 |
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | SMN1; SMN2 252/4885CYP2C19 2307/4885NPC1 4684/4885 |
| US-20250163041-A1 | AZACYCLOALKYL CARBONYL CYCLIC AMINE COMPOUND | NCF1, ELANE, MPO | SMN1; SMN2 1890/4885CYP2C19 840/4885NPC1 732/4885 |
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | SMN1; SMN2 252/4885CYP2C19 2307/4885NPC1 4684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.