SCHEMBL6278596

SCHEMBL6278596

O=C(O)CCCCCSc1cccs1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
PTGER1 P34995 1/20 0.51
PTGFR P43088 1/20 0.51
PTGER3 P43115 1/20 0.51
PTGER2 P43116 1/20 0.51
ALDH1A1 P00352 1/20 0.49
PTGS2 P35354 1/20 0.46
MAPT P10636 2/20 0.43
LTB4R Q15722 4/20 0.42
TSHR P16473 1/20 0.42
HDAC2 Q92769 5/20 0.42
HDAC3 O15379 4/20 0.42
HDAC1 Q13547 4/20 0.42
HDAC8 Q9BY41 4/20 0.42
HDAC6 Q9UBN7 4/20 0.42
HDAC4 P56524 2/20 0.42
HDAC7 Q8WUI4 2/20 0.42
HDAC10 Q969S8 2/20 0.42
HDAC11 Q96DB2 2/20 0.42
HDAC9 Q9UKV0 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3867561 0.98 HPGD (0.53) HPGDPTGER1PTGFRPTGER3PTGER2
SCHEMBL4339780 0.93 ALDH1A1 (0.56) HPGDPTGER1PTGFRPTGER3PTGER2
SCHEMBL5717731 0.86 HPGD (0.47) HPGDPTGER1PTGFRPTGER3PTGER2
SCHEMBL6285438 0.80 PTGDR2 (0.47) HPGDALDH1A1MAPTTSHRNPC1
SCHEMBL6285444 0.80 CA2 (0.44) HPGDPTGER1PTGFRPTGER3PTGER2
SCHEMBL6277977 0.80 CA2 (0.44) HPGDPTGER1PTGFRPTGER3PTGER2
SCHEMBL6278646 0.78 PTGDR2 (0.46) HPGDALDH1A1MAPTTSHRNPC1
SCHEMBL5315566 0.76 FBP1 (0.43) HPGDALDH1A1PTGS2MAPTHDAC1
SCHEMBL20669518 0.76 FBP1 (0.43) HPGDALDH1A1PTGS2MAPTHDAC1
SCHEMBL17372958 0.76 FBP1 (0.43) HPGDALDH1A1PTGS2MAPTHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6861496-B2 Polyhydroxyalkonoate and method of producing same, and ω-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2005-03-01 US claimed
EP-1236754-B1 Polyhydroxyalkanoate and method of producing the same, and omega-(2-thienylsulfanyl)alkanoic acid and method of producing the same CANON KK (JP) 2004-04-28 EP claimed
US-20040062811-A1 Polyhydroxyalkonoate and method of producing same, and w-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA 2004-04-01 US claimed
US-20020164726-A1 Polyhydroxyalkanoate and method of producing same, and w-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2002-11-07 US claimed
EP-1236754-A2 Polyhydroxyalkanoate and method of producing same, and omega-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2002-09-04 EP claimed
US-6861496-B2 Polyhydroxyalkonoate and method of producing same, and ω-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2005-03-01 US disclosed
US-6861496-B2 Polyhydroxyalkonoate and method of producing same, and ω-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2005-03-01 US disclosed
US-6855472-B2 POLYHYDROXYALKANOATE, PRODUCING METHOD THEREFOR, CHARGE CONTROL AGENT CONTAINING SUCH POLYHYDROXYALKANOATE, TONER CONTAINING SUCH CONTROL AGENT AND IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS UTILIZING SUCH TONER CANON KABUSHIKI KAISHA (JP) 2005-02-15 US disclosed
EP-1236754-B1 Polyhydroxyalkanoate and method of producing the same, and omega-(2-thienylsulfanyl)alkanoic acid and method of producing the same CANON KK (JP) 2004-04-28 EP disclosed
US-20040062811-A1 Polyhydroxyalkonoate and method of producing same, and w-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA 2004-04-01 US disclosed
US-20040062811-A1 Polyhydroxyalkonoate and method of producing same, and w-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA 2004-04-01 US disclosed
EP-1254918-B1 Novel polyhydroxyalkanoate, producing method therefor, charge control agent containing such polyhydroxyalkanoate, toner containing such charge control agent and image forming method and image forming apparatus utilizing such toner CANON KK (JP) 2004-03-31 EP disclosed
US-6686439-B2 POLYHYDROXYALKANOATE FOR USE IN CULTURING MICROORGANISMS CANON KABUSHIKI KAISHA (JP) 2004-02-03 US disclosed
US-20030073804-A1 Polyhydroxyalkanoate, producing method therefor charge control agent containing such polyhydroxyalkanoate, toner containing such charge control agent and image forming method and image forming apparatus utilizing such toner CANON KABUSHIKI KAISHA (JP) 2003-04-17 US disclosed
EP-1236754-A3 Polyhydroxyalkanoate and method of producing same, and omega-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2003-02-26 EP disclosed
US-20020164726-A1 Polyhydroxyalkanoate and method of producing same, and w-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2002-11-07 US disclosed
US-20020164726-A1 Polyhydroxyalkanoate and method of producing same, and w-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2002-11-07 US disclosed
EP-1254918-A2 Novel polyhydroxyalkanoate, producing method therefor, charge control agent containing such polyhydroxyalkanoate, toner containing such charge control agent and image forming method and image forming apparatus utilizing such toner CANON KABUSHIKI KAISHA (JP) 2002-11-06 EP disclosed
EP-1236754-A2 Polyhydroxyalkanoate and method of producing same, and omega-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2002-09-04 EP disclosed
EP-1236754-A2 Polyhydroxyalkanoate and method of producing same, and omega-(2-thienylsulfanyl) alkanoic acid and method of producing same CANON KABUSHIKI KAISHA (JP) 2002-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040062811-A1 Polyhydroxyalkonoate and method of producing same, and w-(2-thienylsulfanyl) alkanoic acid and method of producing same HACL2, PAH, TST HPGD 329/4885PTGER1 1756/4885PTGFR 1238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.