SCHEMBL7754428

SCHEMBL7754428

C=CCc1ccc(NC(N)=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.52
ALDH1A1 P00352 4/20 0.50
NPC1 O15118 2/20 0.50
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
GFER P55789 1/20 0.47
KIF11 P52732 4/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 1/20 0.46
KDM4E B2RXH2 2/20 0.44
GLA P06280 1/20 0.42
HSD17B10 Q99714 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
XDH P47989 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11134234 0.83 TGM2 (0.43) ALDH1A1NPC1GAAMAPTMEN1
SCHEMBL9461428 0.82 CYP1A2 (0.40) PEPDALDH1A1NPC1GAAMAPT
SCHEMBL6279031 0.81 TGM2 (0.59) LMNAHSD17B10CYP1A2CYP2D6MAPK1
SCHEMBL7916277 0.81 SMN1; SMN2 (0.53) ALDH1A1NPC1MAPTMEN1KMT2A
SCHEMBL11774737 0.81 CYP1A2 (0.41) ALDH1A1NPC1GAAMAPTMEN1
SCHEMBL27426588 0.80 PEPD (0.59) PEPDALDH1A1NPC1GAAMAPT
SCHEMBL10503744 0.80 THRB (0.49) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL1837826 0.78 PEPD (0.61) PEPDALDH1A1NPC1GAAMAPT
SCHEMBL6285087 0.77 RXFP1 (0.54) ALDH1A1NPC1MAPTKDM4EHSD17B10
SCHEMBL9789610 0.77 POLB (0.67) NPC1MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 PEPD 3259/4885ALDH1A1 3840/4885NPC1 1857/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 PEPD 3259/4885ALDH1A1 3840/4885NPC1 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.