Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280077 | 1.00 | PRCP (0.42) | PRCPMAPTALDH1A1MEN1MAPK1 | |
| SCHEMBL6280066 | 1.00 | PRCP (0.42) | PRCPMAPTALDH1A1MEN1MAPK1 | |
| SCHEMBL6284988 | 0.74 | PRCP (0.44) | PRCPMAPTALDH1A1MEN1MAPK1 | |
| SCHEMBL6289026 | 0.64 | ACHE (0.42) | MAPTALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL6243496 | 0.63 | IDO1 (0.46) | MAPTALDH1A1GAAKDM4EIDO1 | |
| SCHEMBL29915930 | 0.63 | HTR5A (0.43) | ALDH1A1KMT2AIDO1BRD4CREBBP | |
| SCHEMBL2520126 | 0.63 | HTR5A (0.43) | ALDH1A1KMT2AIDO1BRD4CREBBP | |
| SCHEMBL1455790 | 0.62 | IDO1 (0.58) | MAPTALDH1A1GAAKDM4EIDO1 | |
| Hydrochloric Acid SCHEMBL5711485 | 0.62 | HTR5A (0.42) | ALDH1A1KMT2AIDO1BRD4CREBBP | |
| SCHEMBL260994 | 0.60 | BRPF1 (0.53) | MAPTALDH1A1GAAKDM4EIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927294-B1 | Nitrogen-containing heterocycles | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-08-09 | — | — | US | disclosed |