Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289027 | 0.78 | IDO1 (0.41) | IDO1KDM4ENPC1RXFP1ATM | |
| SCHEMBL6280070 | 0.74 | PRCP (0.42) | PRCPIDO1KDM4EGAATDO2 | |
| SCHEMBL6280066 | 0.74 | PRCP (0.42) | PRCPIDO1KDM4EGAATDO2 | |
| SCHEMBL6280077 | 0.74 | PRCP (0.42) | PRCPIDO1KDM4EGAATDO2 | |
| SCHEMBL18025752 | 0.70 | IDO1 (0.51) | IDO1KDM4ENPC1RXFP1ATM | |
| SCHEMBL9541310 | 0.66 | IDO1 (0.50) | IDO1KDM4EATMMTNR1AMEN1 | |
| SCHEMBL6243496 | 0.64 | IDO1 (0.46) | IDO1KDM4ENPC1GAATDO2 | |
| SCHEMBL1455790 | 0.64 | IDO1 (0.58) | IDO1KDM4EGAAATMTDO2 | |
| SCHEMBL166517 | 0.64 | IDO1 (0.43) | IDO1KDM4EGAATDO2MEN1 | |
| SCHEMBL260994 | 0.62 | BRPF1 (0.53) | IDO1KDM4ENPC1GAATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927294-B1 | Nitrogen-containing heterocycles | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-08-09 | — | — | US | disclosed |