Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.74 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480270 | 0.94 | PTGS2 (0.68) | PTGS2CLCN2GAAKMT2AALDH1A1 | |
| SCHEMBL10699208 | 0.88 | CLCN2 (0.66) | PTGS2CLCN2GAAKMT2AALDH1A1 | |
| SCHEMBL13730777 | 0.86 | PTGS2 (0.72) | PTGS2CLCN2GAAKMT2A | |
| SCHEMBL16480275 | 0.84 | PTGS2 (0.58) | PTGS2NLRP3KMT2AALDH1A1ALOX12 | |
| SCHEMBL9932550 | 0.82 | PTGS2 (0.53) | PTGS2GAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11025839 | 0.81 | PTGS2 (0.60) | PTGS2CLCN2GAANLRP3KMT2A | |
| SCHEMBL18734561 | 0.80 | RAPGEF4 (0.56) | PTGS2CLCN2GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL1548694 | 0.80 | ALDH1A1 (0.54) | PTGS2CLCN2GAAKMT2AALDH1A1 | |
| SCHEMBL29611012 | 0.79 | PTGS2 (0.55) | PTGS2CLCN2NLRP3KMT2AALDH1A1 | |
| SCHEMBL2612576 | 0.79 | PTGS2 (0.55) | PTGS2CLCN2NLRP3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268927-B1 | A PROCESS FOR PRODUCTION OF PAPER MATERIALS WITH IMPROVED WET STRENGTH | NOVOZYMES AS (DK) | 2005-10-26 | — | — | EP | disclosed |