Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548694 | 0.89 | ALDH1A1 (0.54) | PTGS2MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16480270 | 0.84 | PTGS2 (0.68) | PTGS2MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18944529 | 0.84 | MAPT (0.45) | PTGS2MAPTHTTALDH1A1GAA | |
| SCHEMBL11636082 | 0.83 | SMN1; SMN2 (0.50) | PTGS2MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6280428 | 0.82 | PTGS2 (0.74) | PTGS2MAPTHTTALDH1A1GAA | |
| SCHEMBL29511793 | 0.82 | HTT (0.59) | PTGS2MAPTHTTALDH1A1GAA | |
| SCHEMBL183017 | 0.82 | HTT (0.59) | PTGS2MAPTHTTALDH1A1GAA | |
| SCHEMBL28227625 | 0.82 | HTT (0.47) | PTGS2MAPTHTTALDH1A1RAB9A | |
| SCHEMBL5321487 | 0.81 | PTGS2 (0.44) | PTGS2MAPTHTTALDH1A1GAA | |
| SCHEMBL7166134 | 0.80 | PTGS2 (0.77) | PTGS2PTGS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9515268-B2 | Aromatic amine derivatives and preparation method, uses and organic electroluminescent devices thereof | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-12-06 | — | — | US | disclosed |
| US-9515268-B2 | Aromatic amine derivatives and preparation method, uses and organic electroluminescent devices thereof | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-12-06 | — | — | US | disclosed |
| US-9515268-B2 | Aromatic amine derivatives and preparation method, uses and organic electroluminescent devices thereof | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-12-06 | — | — | US | disclosed |
| EP-2699241-B1 | ANTIVIRAL COMPOUNDS | PROSETTA ANTIVIRAL INC (US) | 2016-07-27 | — | — | EP | disclosed |
| EP-2585073-B1 | ANTIVIRAL COMPOUNDS | PROSETTA ANTIVIRAL INC (US) | 2016-04-27 | — | — | EP | disclosed |
| US-20160087221-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD, USES AND ORGANIC ELECTROLUMINESCENT DEVICES THEREOF | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-03-24 | — | — | US | disclosed |
| US-20160087221-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD, USES AND ORGANIC ELECTROLUMINESCENT DEVICES THEREOF | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-03-24 | — | — | US | disclosed |
| US-20160087221-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD, USES AND ORGANIC ELECTROLUMINESCENT DEVICES THEREOF | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-03-24 | — | — | US | disclosed |
| CN-103992335-B | Aromatic amine derivative, and preparation method, use and organic electroluminescent device thereof | BOE TECHNOLOGY GROUP CO LTD | 2015-04-08 | — | — | CN | disclosed |
| US-8828986-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-09-09 | — | — | US | disclosed |
| CN-103992335-A | Aromatic amine derivative, and preparation method, use and organic electroluminescent device thereof | BOE TECHNOLOGY GROUP CO LTD | 2014-08-20 | — | — | CN | disclosed |
| US-20140206863-A1 | Copper Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-07-24 | — | — | US | disclosed |
| US-8785434-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120270854-A1 | Antiviral Compounds | PROSETTA ANTIVIRAL INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120157435-A1 | Antiviral Compounds | PROSETTA ANTIVIRAL INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157435-A1 | Antiviral Compounds | MAVS, ZC3HAV1, EIF2AK2 | PTGS2 3110/4885MAPT 693/4885HTT 1053/4885 |
| US-20160087221-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD, USES AND ORGANIC ELECTROLUMINESCENT DEVICES THEREOF | C1S, C5, C9 | PTGS2 3409/4885MAPT 2759/4885HTT 2248/4885 |
| US-20120270854-A1 | Antiviral Compounds | HAVCR2, MAVS, EIF2AK2 | PTGS2 3410/4885MAPT 1569/4885HTT 259/4885 |
| US-20140206863-A1 | Copper Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | SOD1, COPE, MMS19 | PTGS2 802/4885MAPT 1708/4885HTT 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.