Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039033 | 0.79 | ESR1 (0.67) | KDM4EGAADRD2HTR2AHTR2C | |
| SCHEMBL29218370 | 0.79 | KDM4E (0.50) | KDM4EGAADRD2HTR2AHTR2C | |
| SCHEMBL28906373 | 0.79 | DRD2 (0.62) | KDM4EGAADRD2HTR2AHTR2C | |
| SCHEMBL13698928 | 0.77 | ALDH1A1 (0.64) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL29353160 | 0.77 | ALDH1A1 (0.64) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL29955809 | 0.76 | KDM4E (0.51) | KDM4EGAADRD2HTR2AHTR2C | |
| Carbazole SCHEMBL22118218 | 0.73 | ALDH1A1 (0.56) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL8723074 | 0.71 | IMPDH2 (0.54) | KDM4EGAADRD2HTR2AHTR2C | |
| SCHEMBL7593338 | 0.70 | KDM4E (0.62) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL607342 | 0.70 | MMP2 (0.51) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005179218-A | SKIN CARE PREPARATION FOR EXTERNAL USE CONTAINING MERCAPTOINDOLE DERIVATIVE | NOMURA:KK | 2005-07-07 | — | — | JP | disclosed |