Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814837 | 0.83 | GAA (0.44) | SIGMAR1AMPD2LMNAGAACHEK1 | |
| SCHEMBL11807403 | 0.81 | KDM4E (0.46) | SIGMAR1AMPD2MAPTHTTSMN1; SMN2 | |
| SCHEMBL16367848 | 0.77 | ENPP2 (0.47) | SMN1; SMN2ALDH1A1KDM4ECHEK1 | |
| SCHEMBL11811379 | 0.74 | KMT2A (0.47) | SIGMAR1AMPD2MAPTSMN1; SMN2LMNA | |
| SCHEMBL29668629 | 0.74 | SIGMAR1 (0.79) | SIGMAR1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL20238106 | 0.74 | SIGMAR1 (0.79) | SIGMAR1TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8204263 | 0.73 | ALDH1A1 (0.47) | SIGMAR1TDP1LMNAALDH1A1CYP11B1 | |
| SCHEMBL11119636 | 0.73 | CHEK1 (0.44) | ALDH1A1CHEK1TAAR1TSHRCYP1A2 | |
| SCHEMBL16365587 | 0.73 | CHEK1 (0.41) | LMNACHEK1KMT2A | |
| Maleic Acid SCHEMBL27879743 | 0.72 | AMPD2 (0.43) | SIGMAR1AMPD2CYP2C19LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975357-A | SUBSTITUTED PIPERIDINES | SANKYO COMPANY LIMITED (JA) | 1976-08-17 | — | — | US | disclosed |