Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046926 | 0.84 | GPR35 (0.46) | GPR35MAPK1HPGDALDH1A1TP53 | |
| SCHEMBL3274968 | 0.83 | SNCA (0.39) | GPR35MAPK1HPGDALDH1A1TP53 | |
| SCHEMBL2886629 | 0.81 | CYP3A4 (0.39) | GPR35MAPK1HPGDALDH1A1TP53 | |
| SCHEMBL4902091 | 0.78 | CA12 (0.34) | GPR35MAPK1HPGDALDH1A1TP53 | |
| SCHEMBL6282528 | 0.76 | TSHR (0.42) | GPR35MAPK1HPGDALDH1A1TSHR | |
| SCHEMBL1822058 | 0.76 | ALDH1A1 (0.46) | GPR35MAPK1HPGDALDH1A1TP53 | |
| SCHEMBL1891926 | 0.76 | TSHR (0.44) | GPR35HPGDALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6036448 | 0.74 | ALDH1A1 (0.42) | MAPK1ALDH1A1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL1356676 | 0.73 | ALDH1A1 (0.47) | MAPK1ALDH1A1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL11835122 | 0.73 | GPR35 (0.60) | GPR35MAPK1HPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362243-B2 | Method for selective localization of active agents at and in mitochondria and corresponding active agents | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2013-01-29 | — | — | US | disclosed |
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2010-01-14 | — | — | US | disclosed |
| EP-0686043-B1 | COMPOSITIONS AND METHODS OF APPLICATION OF REACTIVE ANTIVIRAL POLYMERS | WANG JUI H (US) | 1999-06-23 | — | — | EP | disclosed |
| EP-0686043-A4 | COMPOSITIONS AND METHODS OF APPLICATION OF REACTIVE ANTIVIRAL POLYMERS | WANG JUI H (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5496546-A | INHIBITORS OF RIBONUCLEASE OF TRANSCRIPTASE | Wang, Jui H. (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0686043-A1 | COMPOSITIONS AND METHODS OF APPLICATION OF REACTIVE ANTIVIRAL POLYMERS | WANG, Jui, H. (US) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994019012-A2 | COMPOSITIONS AND METHODS OF APPLICATION OF REACTIVE ANTIVIRAL POLYMERS | WANG JUI H (US) | 1994-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | TFB2M, TFAM, SHMT2 | GPR35 1586/4885MAPK1 3837/4885HPGD 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.