Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283289 | 0.85 | MASP2 (0.40) | MASP2RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL6288495 | 0.83 | RAB9A (0.40) | MASP2RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL6279512 | 0.83 | KDM4E (0.37) | RAB9AGAAKDM4EALDH1A1HPGD | |
| SCHEMBL6287816 | 0.83 | XDH (0.39) | RAB9AGAAKDM4EALDH1A1HPGD | |
| SCHEMBL6287852 | 0.79 | PIN1 (0.38) | MASP2RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6288661 | 0.77 | ADORA1 (0.37) | MASP2RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL6286506 | 0.76 | MAPT (0.37) | MASP2RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL6279830 | 0.72 | KDM4E (0.39) | RAB9AGAAKDM4EALDH1A1HPGD | |
| SCHEMBL2273224 | 0.69 | RAB9A (0.42) | MASP2RAB9AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL6288020 | 0.68 | KDM4E (0.41) | RAB9AGAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923929-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS OXIDATION AGENTS, AND DYEING METHOD; PYRAZOLOAZOLES | OREAL (FR) | 2004-05-12 | — | — | EP | claimed |
| US-20020152558-A1 | Compositions for dyeing keratinous fibers comprising pyrazoloazoles; their use in dyeing as oxidation base and dyeing process; and novel pyrazoloazoles | L'OREAL | 2002-10-24 | — | — | US | claimed |
| US-6379397-B2 | CAPABLE OF GENERATING INTENSE COLORINGS IN VARIED SHADES | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6855827-B2 | Compositions for dyeing keratinous fibers comprising pyrazoloazoles; their use in dyeing as oxidation base and dyeing process; and novel pyrazoloazoles | L'ORÉAL (FR) | 2005-02-15 | — | — | US | disclosed |
| US-20020152558-A1 | Compositions for dyeing keratinous fibers comprising pyrazoloazoles; their use in dyeing as oxidation base and dyeing process; and novel pyrazoloazoles | L'OREAL | 2002-10-24 | — | — | US | disclosed |
| US-6379397-B2 | CAPABLE OF GENERATING INTENSE COLORINGS IN VARIED SHADES | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |
| US-20020007520-A1 | COMPOSITIONS FOR DYEING KERATINOUS FIBERS COMPRISING PYRAZOLOAZOLES; THEIR USE IN DYEING AS OXIDATION BASE AND DYEING PROCESS; AND NOVEL PYRAZOLOAZOLES | L'OREAL S.A. (FR) | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007520-A1 | COMPOSITIONS FOR DYEING KERATINOUS FIBERS COMPRISING PYRAZOLOAZOLES; THEIR USE IN DYEING AS OXIDATION BASE AND DYEING PROCESS; AND NOVEL PYRAZOLOAZOLES | KRT18, ZYX, TUBB3 | MASP2 4509/4885RAB9A 2652/4885GAA 4695/4885 |
| US-20020152558-A1 | Compositions for dyeing keratinous fibers comprising pyrazoloazoles; their use in dyeing as oxidation base and dyeing process; and novel pyrazoloazoles | KRT18, ZYX, TUBB3 | MASP2 4509/4885RAB9A 2652/4885GAA 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.