Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694492 | 0.92 | TDP1 (0.53) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL14667559 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL6284097 | 0.84 | HTR2A (0.58) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL10368677 | 0.84 | ALDH1A1 (0.51) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL17102847 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL5058671 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL27911679 | 0.81 | GPR84 (0.59) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL5066540 | 0.81 | GPR84 (0.65) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL5058656 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL6516641 | 0.81 | HTR2A (0.58) | ALDH1A1LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107258-A1 | Auxinic analogues of indole-3-acetic acid | Life Technologies Corporation | 2005-05-19 | — | — | US | claimed |
| US-6815205-B2 | GENERATING PLANT ROOTS | INVITROGEN CORPORATION | 2004-11-09 | — | — | US | claimed |
| US-20030087762-A1 | Auxinic analogues of indole-3-acetic acid | LIFE TECHNOLOGIES, INC. | 2003-05-08 | — | — | US | claimed |
| EP-0866850-A4 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES INC (US) | 2000-11-22 | — | — | EP | claimed |
| EP-0866850-A1 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES, INC. (US) | 1998-09-30 | — | — | EP | claimed |
| WO-1997020034-A9 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | — | 1997-10-16 | — | — | WO | claimed |
| WO-1997020034-A1 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES, INC. (US) | 1997-06-05 | — | — | WO | claimed |
| US-20050107258-A1 | Auxinic analogues of indole-3-acetic acid | Life Technologies Corporation | 2005-05-19 | — | — | US | disclosed |
| US-6815205-B2 | GENERATING PLANT ROOTS | INVITROGEN CORPORATION | 2004-11-09 | — | — | US | disclosed |
| US-20030087762-A1 | Auxinic analogues of indole-3-acetic acid | LIFE TECHNOLOGIES, INC. | 2003-05-08 | — | — | US | disclosed |
| US-6361999-B1 | AMELIORATING DETRIMENTAL EFFECTS OF STRESS ON A PLANT OR PLANT TISSUE, SUCH AS ENVIRONMENTAL STRESS, PHYSICAL STRESS, CHEMICAL STRESS, FROM POLLUTION, CONTAMINATION, DROUGHT, AND LIGHT BY CONTACTING WITH AUXINIC INDOLE ACETIC ACID COMPOUND | LIFE TECHNOLOGIES, INC. | 2002-03-26 | — | — | US | disclosed |
| EP-0866850-A4 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES INC (US) | 2000-11-22 | — | — | EP | disclosed |
| EP-0866850-A1 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES, INC. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997020034-A9 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | — | 1997-10-16 | — | — | WO | disclosed |
| WO-1997020034-A1 | AUXINIC ANALOGUES OF INDOLE-3-ACETIC ACID | LIFE TECHNOLOGIES, INC. (US) | 1997-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087762-A1 | Auxinic analogues of indole-3-acetic acid | AADAC, AADAT, AANAT | ALDH1A1 938/4885LMNA 4471/4885HTT 1926/4885 |
| US-20050107258-A1 | Auxinic analogues of indole-3-acetic acid | AADAC, AADAT, AANAT | ALDH1A1 1052/4885LMNA 4462/4885HTT 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.