Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisindione SCHEMBL49379 | 0.85 | RAB9A (1.00) | RAB9AHPGDMAPTTP53NPC1 | |
| Anisindione SCHEMBL29688105 | 0.85 | RAB9A (1.00) | RAB9AHPGDMAPTTP53NPC1 | |
| SCHEMBL14939987 | 0.81 | RAB9A (0.54) | RAB9AHPGDMAPTTP53NPC1 | |
| SCHEMBL9790520 | 0.79 | ACHE (0.54) | RAB9AHPGDMAPTTP53NPC1 | |
| SCHEMBL6356064 | 0.79 | RAB9A (0.59) | RAB9AHPGDMAPTTP53NPC1 | |
| SCHEMBL19320919 | 0.78 | MAPT (0.50) | RAB9AHPGDMAPTTP53NPC1 | |
| SCHEMBL11808306 | 0.77 | HPGD (0.45) | RAB9AHPGDMAPTTP53NPC1 | |
| SCHEMBL11810507 | 0.76 | RAB9A (0.47) | RAB9AHPGDMAPTTP53NPC1 | |
| SCHEMBL14665734 | 0.75 | MAOA (0.58) | RAB9AHPGDMAPTTP53NPC1 | |
| SCHEMBL8958196 | 0.74 | RAB9A (0.67) | RAB9AHPGDMAPTTP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903238-B2 | Substituted indenones as estrogenic agents | WYETH (US) | 2005-06-07 | — | — | US | disclosed |
| US-6838584-B2 | Estrogen receptor modulators | MERCK & CO., INC. (US) | 2005-01-04 | — | — | US | disclosed |
| US-20040162304-A1 | Estrogen receptor modulators | MERCK & CO., INC. | 2004-08-19 | — | — | US | disclosed |
| EP-1387821-A2 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2004-02-11 | — | — | EP | disclosed |
| US-20030166643-A1 | Substituted indenones as estrogenic agents | WYETH | 2003-09-04 | — | — | US | disclosed |
| WO-2002091993-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162304-A1 | Estrogen receptor modulators | ESRRA, GPER1, ESRRB | RAB9A 3951/4885HPGD 784/4885MAPT 843/4885 |
| US-20030166643-A1 | Substituted indenones as estrogenic agents | GPER1, ESR2, ESR1 | RAB9A 3245/4885HPGD 1912/4885MAPT 3793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.