Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 6/20 | 0.42 |
| ▸ | NOS1 | P29475 | 6/20 | 0.42 |
| ▸ | NOS2 | P35228 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284562 | 0.81 | QRFPR (0.45) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL6279600 | 0.78 | NOS1 (0.57) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL6279596 | 0.78 | NOS1 (0.57) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL6970126 | 0.78 | QRFPR (0.47) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL6970122 | 0.78 | QRFPR (0.47) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL7222691 | 0.68 | NOS1 (0.54) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL7222678 | 0.68 | NOS1 (0.54) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL7690137 | 0.66 | NOS3 (0.48) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL7562858 | 0.66 | QRFPR (0.71) | QRFPRNOS3NOS1NOS2 | |
| SCHEMBL7697635 | 0.66 | NOS3 (0.53) | QRFPRNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887891-B2 | Derivatives of lipoic acid, their preparation, their use as medicaments and the pharmaceutical compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2005-05-03 | — | — | US | disclosed |
| US-20040019084-A1 | New derivatives of lipoic acid, their preparation, their use as medicaments and the pharmaceutical compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTIFIQUES (S.C.R.A.S) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019084-A1 | New derivatives of lipoic acid, their preparation, their use as medicaments and the pharmaceutical compositions containing them | NOS1, NOS2, LPO | QRFPR 3937/4885NOS3 5/4885NOS1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.