Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284988 | 0.78 | PRCP (0.44) | IDO1KDM4ENPC1RXFP1MAPT | |
| SCHEMBL18025752 | 0.71 | IDO1 (0.51) | IDO1KDM4ENPC1RXFP1MAPT | |
| SCHEMBL9541310 | 0.67 | IDO1 (0.50) | IDO1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6220534 | 0.65 | BRPF1 (0.52) | IDO1KDM4ENPC1MAPTTDP1 | |
| SCHEMBL19054962 | 0.63 | BRPF1 (0.53) | IDO1KDM4ENPC1MAPTTDP1 | |
| SCHEMBL260994 | 0.63 | BRPF1 (0.53) | IDO1KDM4ENPC1MAPTTDP1 | |
| SCHEMBL30088920 | 0.63 | BRPF1 (0.53) | IDO1KDM4ENPC1MAPTTDP1 | |
| SCHEMBL23836089 | 0.63 | IDO1 (0.46) | IDO1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL2520126 | 0.63 | HTR5A (0.43) | IDO1KMT2ABRPF1CREBBPALDH1A1 | |
| SCHEMBL29915930 | 0.63 | HTR5A (0.43) | IDO1KMT2ABRPF1CREBBPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927294-B1 | Nitrogen-containing heterocycles | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-08-09 | — | — | US | disclosed |