SCHEMBL6285087

SCHEMBL6285087

C=CCc1ccc(NC(=O)C(=C)C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.54
TDP1 Q9NUW8 2/20 0.45
FGFR1 P11362 1/20 0.44
FGFR4 P22455 1/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
BAZ1A Q9NRL2 1/20 0.41
TP53 P04637 3/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7916277 0.84 SMN1; SMN2 (0.53) TDP1CYP1A2HSD17B10POLBL3MBTL1
SCHEMBL439393 0.82 RXFP1 (0.74) RXFP1TDP1FGFR1FGFR4MAPK1
SCHEMBL2452374 0.81 RXFP1 (0.59) RXFP1TDP1FGFR1FGFR4POLB
SCHEMBL13802232 0.81 RXFP1 (0.59) RXFP1TDP1FGFR1FGFR4SMN1; SMN2
SCHEMBL11430538 0.79 RXFP1 (0.57) RXFP1TDP1FGFR1FGFR4POLB
SCHEMBL6415721 0.79 RXFP1 (0.57) RXFP1TDP1FGFR1FGFR4POLB
SCHEMBL19854526 0.79 THRA (0.53) RXFP1POLBTHRATHRB
SCHEMBL11134234 0.79 TGM2 (0.43) TDP1CYP1A2CYP2D6MAPK1HSD17B10
SCHEMBL8604610 0.78 RXFP1 (0.56) RXFP1TDP1FGFR1FGFR4POLB
SCHEMBL9067803 0.78 RXFP1 (0.56) RXFP1TDP1HSD17B10POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890625-B2 Aqueous adhesive WACKER CHEMICAL CORP (US) 2014-05-21 EP disclosed
EP-0890625-B1 Aqueous adhesive AIR PROD & CHEM (US) 2005-11-23 EP disclosed
EP-1411097-A1 Water-based adhesive compositions using waterborne polyesters AIR PRODUCTS POLYMERS, L.P. (US) 2004-04-21 EP disclosed
US-20040072003-A1 Water-based adhesive compositions using waterborne polyesters AIR PRODUCTS POLYMERS, L.P. 2004-04-15 US disclosed
US-6063858-A COMPRISING ETHYLENE-VINYL ACETATE COPOLYMER STABILIZED BY POLYVILYL ALCOHOL AND A CAST FILM; PLASTICS PACKAGING MATERIALS AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-05-16 US disclosed
US-5872181-A AN ADHESIVE COMPRISES VINYL ACETATE-ETHYLENE COPOLYMER OR TERPOLYMER WITH ETHYLENICALLY UNSATURATED COPOLYMERIZABLE MONOMER, CAST FILM OF ADHESIVE HAVE PREFERENTIAL TENSILE STORAGE MODULUS AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-02-16 US disclosed
EP-0890625-A1 Aqueous adhesive AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-01-13 EP disclosed
US-5500251-A (METH)ACRYLAMIDES AND MALEIMIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1996-03-19 US disclosed
US-5500251-A (METH)ACRYLAMIDES AND MALEIMIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1996-03-19 US disclosed