Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.39 |
| ▸ | SELE | P16581 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815037 | 0.88 | MAOB (0.44) | ALDH1A1KDM4ELSSMAOBTUBB4A | |
| SCHEMBL5045447 | 0.79 | APP (0.49) | ALDH1A1KDM4EHPGDLSSMAOB | |
| SCHEMBL6279648 | 0.79 | NOD2 (0.50) | ALDH1A1KDM4EHPGDMAOBMAOA | |
| SCHEMBL22871555 | 0.79 | MAPK13 (0.44) | ALDH1A1LSSMAOBTUBB4ATUBB | |
| SCHEMBL5043116 | 0.79 | LSS (0.54) | ALDH1A1KDM4EHPGDLSSMAOB | |
| SCHEMBL4744399 | 0.79 | MIF (0.48) | LSSMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL6281250 | 0.79 | XDH (0.49) | ALDH1A1KDM4EHPGDLSSMAOB | |
| SCHEMBL8341333 | 0.79 | PIN1 (0.51) | ALDH1A1KDM4EHPGDMAOBMAPT | |
| SCHEMBL6984133 | 0.78 | MAPT (0.44) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6984794 | 0.78 | MKNK1 (0.44) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921827-B2 | Process for preparing 3-aryl-benzo{b} thiophenes | ELI LILLY AND COMPANY (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040132775-A1 | Process for preparing 3-aryl-benzo{b} thiophenes | LUKE WAYNE DOUGLAS (US) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132775-A1 | Process for preparing 3-aryl-benzo{b} thiophenes | TBCB, CYP1B1, TST | ALDH1A1 2025/4885KDM4E 1557/4885HPGD 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.