Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 14/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992997 | 0.86 | CHRNB2 (0.50) | CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL31395590 | 0.83 | ALDH1A1 (0.49) | GPR88NPC1MTORTP53CYP3A4 | |
| SCHEMBL6281442 | 0.81 | HIF1A (0.40) | GPR88TP53MAPK1KDM4ELMNA | |
| SCHEMBL6682144 | 0.81 | CHRNB2 (0.45) | CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL408132 | 0.80 | CHRNB2 (0.50) | CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9797252 | 0.79 | LMNA (0.60) | CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6935832 | 0.79 | CYP2C9 (0.49) | GPR88CYP2C9CYP2C19KDM4EHPGD | |
| Ammonia Solution, Strong SCHEMBL28712158 | 0.79 | CHRNB2 (0.49) | CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25378071 | 0.77 | GPR88 (0.44) | GPR88 | |
| SCHEMBL7785554 | 0.77 | LTA4H (0.50) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900273-B1 | Low-hygroscopicity low-birefringence resin compositions, molding material obtained therefrom, sheet or film, and optical part | HITACHI CHEMICAL CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20040220342-A1 | Low-hygroscopicity low-birefringence resin compositions, molding material, sheet or film obtained therefrom, and optical part | YAMASHITA YUKIHIKO (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1205517-A1 | LOW-HYGROSCOPICITY LOW-BIREFRINGENCE RESIN COMPOSITIONS, MOLDING MATERIAL OBTAINED THEREFROM, SHEET OR FILM, AND OPTICAL PART | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |