Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907633 | 0.79 | CA12 (0.49) | AAK1CA12CA1CA9PRMT5 | |
| SCHEMBL16042474 | 0.78 | CA12 (0.43) | AAK1CA12CA1CA9PRMT5 | |
| SCHEMBL6096438 | 0.78 | MAPT (0.44) | CA12CA1CA9PPARGALDH1A1 | |
| SCHEMBL3767805 | 0.78 | AAK1 (0.45) | AAK1CA12CA1CA9PRMT5 | |
| SCHEMBL31061614 | 0.77 | ALDH1A1 (0.48) | AAK1CA12CA1CA9PRMT5 | |
| SCHEMBL65972 | 0.77 | ALDH1A1 (0.48) | AAK1CA12CA1CA9PRMT5 | |
| SCHEMBL12072363 | 0.77 | CA12 (0.49) | AAK1CA12CA1CA9PRMT5 | |
| SCHEMBL20936579 | 0.76 | CA12 (0.44) | AAK1CA12CA1CA9PRMT5 | |
| SCHEMBL6096016 | 0.76 | CA12 (0.41) | CA12CA1CA9PPARGALDH1A1 | |
| SCHEMBL15897919 | 0.76 | AAK1 (0.45) | AAK1CA12CA1CA9PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6840965-B2 | P-aminophenols and colorants containing said compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-01-11 | — | — | US | disclosed |
| US-6749644-B2 | DEVELOPER AND COUPLER; WIDE RANGE OF DIFFERENT COLOR SHADES FROM BLOND TO BROWN, PURPLE, VIOLET AND EVEN BLUE AND BLACK; INTENSITY | WELLA AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| US-6592631-B2 | Useful as developer compounds in oxidation dye compositions for keratin fibers. | WELLA AG (DE) | 2003-07-15 | — | — | US | disclosed |
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | disclosed |
| US-20020166180-A1 | 2-hydroxy-5-amino-biphenyl-derivatives and oxidative hair colouring agents containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-14 | — | — | US | disclosed |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2001-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | ALPP, GSTP1, GPX4 | AAK1 2595/4885CA12 2067/4885CA1 3303/4885 |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | KRT18, AASDHPPT, S100P | AAK1 1282/4885CA12 3181/4885CA1 3488/4885 |
| US-20020166180-A1 | 2-hydroxy-5-amino-biphenyl-derivatives and oxidative hair colouring agents containing said compounds | AHR, KRT18, HMOX2 | AAK1 2550/4885CA12 4045/4885CA1 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.