Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694499 | 0.71 | MEN1 (0.45) | ALDH1A1KDM4EMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2302687 | 0.70 | ALDH1A1 (0.38) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL28610364 | 0.69 | MTNR1A (0.41) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL19993845 | 0.67 | MTNR1A (0.42) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL27726500 | 0.67 | IDO1 (0.53) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9390206 | 0.66 | KDM1A (0.47) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL1025256 | 0.66 | KDM1A (0.43) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL21889682 | 0.66 | PLA2G6 (0.43) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL27705886 | 0.66 | MAPK1 (0.43) | MAPK1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL6288863 | 0.64 | PLA2G6 (0.56) | MAPK1ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956055-B2 | Substituted γ-lactone compounds as NMDA-antagonists | GRUNENTHAL GMBH (DE) | 2005-10-18 | — | — | US | disclosed |