SCHEMBL2302687

SCHEMBL2302687

O=C1OC=CC1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPT P10636 4/20 0.35
LMNA P02545 3/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR2B P41595 1/20 0.35
CA2 P00918 1/20 0.34
GAA P10253 4/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 5/20 0.33
RAB9A P51151 1/20 0.32
SLC6A3 Q01959 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KMT2A Q03164 3/20 0.32
POLB P06746 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 2/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31590688 0.88 EPHX1 (0.38) ALDH1A1MAPTTP53CYP1A2KDM4E
SCHEMBL32670843 0.77 CYP19A1 (0.40) ALDH1A1MAPTLMNACYP1A2CYP3A4
SCHEMBL296804 0.71 SLC6A2 (0.38) SLC6A3
SCHEMBL1354899 0.71 ALDH1A1 (0.36) ALDH1A1MAPTLMNATSHRKDM4E
SCHEMBL16116061 0.71 LMNA (0.33) ALDH1A1MAPTLMNAMAPK1TP53
SCHEMBL30608092 0.71 CA2 (0.40) ALDH1A1MAPTLMNAMAPK1TP53
SCHEMBL6288864 0.70 MAPK1 (0.43) ALDH1A1MAPTLMNAMAPK1TP53
SCHEMBL9694499 0.69 MEN1 (0.45) ALDH1A1MAPTHTR2BCA2KDM4E
SCHEMBL17923887 0.67 SIRT1 (0.37) ALDH1A1MAPTLMNAMAPK1TP53
SCHEMBL8701734 0.65 HRH1 (0.36) GAATSHRSLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081784-A Whitening compound containing pyridine amide structure and preparation method and application thereof 东北农业大学 2025-06-03 CN disclosed
CN-115851636-B Mutant PDS polypeptide and application thereof 山东舜丰生物科技有限公司 2025-03-21 CN disclosed
CN-118599783-A Hybridoma cell strain secreting furbenone monoclonal antibody and application thereof 江南大学 2024-09-06 CN disclosed
CN-117448102-A Preparation method of soybean paste flavored soy sauce wine 张仲安 2024-01-26 CN disclosed
CN-115851636-A Mutant PDS polypeptide and application thereof 山东舜丰生物科技有限公司 2023-03-28 CN disclosed
US-20150208645-A1 PHYTOSANITARY COMPOSITIONS COMPRISING AN ETHER-AMIDE COMPOUND RHODIA OPERATIONS (FR) 2015-07-30 US disclosed
EP-1594438-B1 Use of an inhibitor of 15-hydroxyprostaglandin dehydrogenase in order to stimulate pigmentation of the skin or hair OREAL (FR) 2013-07-17 EP disclosed
US-7994176-B2 Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 ELI LILLY AND COMPANY (US) 2011-08-09 US disclosed
EP-2021337-B1 INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 LILLY CO ELI (US) 2010-01-13 EP disclosed
CN-100486573-C Nitrocessed and nitrosylated cyclooxygenase-2 inhibitors, compositions, and uses thereof NITROMED INC (US) 2009-05-13 CN disclosed
CN-1434712-A Nitrosated and nitrosylated cyclooxygenase-2 inhibitors compositions and methods of use NITROMED INC (US) 2003-08-06 CN disclosed
US-6011060-A TREATING A DISEASE MEDIATED BY ACTIVATION OF THE TUMOR NECROSIS FACTOR SCHERING AKTIENGESELLSCHAFT (DE) 2000-01-04 US disclosed
US-6011060-A TREATING A DISEASE MEDIATED BY ACTIVATION OF THE TUMOR NECROSIS FACTOR SCHERING AKTIENGESELLSCHAFT (DE) 2000-01-04 US disclosed
US-6011060-A TREATING A DISEASE MEDIATED BY ACTIVATION OF THE TUMOR NECROSIS FACTOR SCHERING AKTIENGESELLSCHAFT (DE) 2000-01-04 US disclosed
EP-0900212-A1 CHIRAL PHENYLDIHYDROFURANONES AS PDE-IV INHIBITORS SCHERING AKTIENGESELLSCHAFT (DE) 1999-03-10 EP disclosed
WO-1997040032-A1 CHIRAL PHENYLDIHYDROFURANONES AS PDE-IV INHIBITORS SCHERING AKTIENGESELLSCHAFT (DE) 1997-10-30 WO disclosed
US-5422247-A A grampositive or mutants of BLAKESLEA TRISPORA forming a mated culture product with gramnegative BLAKESLEA TRISPORA UNIVERSAL FOODS CORPORATION (US) 1995-06-06 US disclosed
US-5360730-A Zeaxanthin producing strains of Neospongiococcum Excentricum UNIVERSAL FOODS CORPORATION (US) 1994-11-01 US disclosed
US-5328845-A Fungal negative microorganism capable of producing high levels of beta-carotene UNIVERSAL FOODS CORPORATION (US) 1994-07-12 US disclosed
WO-1993020183-A1 METHOD FOR PRODUCING BETA-CAROTENE USING A FUNGAL MATED CULTURE UNIVERSAL FOODS CORPORATION (US) 1993-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150208645-A1 PHYTOSANITARY COMPOSITIONS COMPRISING AN ETHER-AMIDE COMPOUND ACER2, LSS, FNTA ALDH1A1 4758/4885MAPT 63/4885LMNA 795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.