Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016497 | 1.00 | HTT (0.60) | HTTMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL624930 | 0.86 | SMN1; SMN2 (0.61) | HTTMAPTMEN1KMT2AGSK3B | |
| SCHEMBL29799615 | 0.86 | SMN1; SMN2 (0.61) | HTTMAPTMEN1KMT2AGSK3B | |
| SCHEMBL16809415 | 0.85 | MEN1 (0.49) | HTTMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL1415307 | 0.85 | HPGDS (0.48) | HTTMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL563749 | 0.85 | GSK3B (0.59) | HTTMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2096737 | 0.84 | HPGDS (0.57) | HTTMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL29514451 | 0.84 | HTT (0.62) | HTTMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL5743965 | 0.84 | HTT (0.62) | HTTMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL3610282 | 0.84 | HTT (0.62) | HTTMAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745812-A | Preparation method of 2-amino-1- (2,5-dimethoxyphenyl) ethanol | 成都沣德煜晟医药科技有限公司 | 2023-03-07 | — | — | CN | claimed |
| US-20140235863-A1 | SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-08-21 | — | — | US | claimed |
| US-8703194-B2 | Stimulus-responsive biodegradable polymers and methods of preparation | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-04-22 | — | — | US | claimed |
| US-8658209-B2 | — | — | 2014-02-25 | — | — | US | claimed |
| US-20090123544-A1 | STIMULUS-RESPONSIVE BIODEGRADABLE POLYMERS AND METHODS OF PREPARATION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2009-05-14 | — | — | US | claimed |
| US-7094928-B2 | Process for the synthesis of (±) 2-Amino-N-[2,(2,5-dimethoxy phenyl)-2-hydroxyethyl] acetamide monohydrochloride | SANMAR SPECIALTY CHEMICALS LTD. (IN) | 2006-08-22 | — | — | US | claimed |
| EP-1465860-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF ( ) 2-AMINO-N-[2,(S,5-DIMETHOXYPHENYL)-2-HYDROXYETHYL] ACETAMIDE MONOHYDROCHLORIDE | Sanmar Speciality Chemicals Ltd (IN) | 2004-10-13 | — | — | EP | claimed |
| EP-1465860-A4 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF ( ) 2-AMINO-N-[2,(S,5-DIMETHOXYPHENYL)-2-HYDROXYETHYL] ACETAMIDE MONOHYDROCHLORIDE | SANMAR SPECIALITY CHEMICALS LT (IN) | 2004-10-13 | — | — | EP | claimed |
| US-20040198836-A1 | Process for the synthesis of (+) 2-amino-n-{2, (2,5-dimethoxy phenyl)-2-hydroxyethyl} acetamide monohydrochloride | SANMAR SPECIALTY CHEMICALS LTD. (IN) | 2004-10-07 | — | — | US | claimed |
| WO-2004018409-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF (±) 2-AMINO-N-[2,(S,5-DIMETHOXYPHENYL)-2-HYDROXYETHYL] ACETAMIDE MONOHYDROCHLORIDE | SANMAR SPECIALITY CHEMICALS LTD (IN) | 2004-03-04 | — | — | WO | claimed |
| CN-1013444-B | PROCESS FOR THE PREPARATION OF A NOVEL CLASS OF HYPOGLYCEMIC AGENTS | LILLY CO ELI (US) | 1991-08-07 | — | — | CN | claimed |
| US-11958844-B2 | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-04-16 | — | — | US | disclosed |
| EP-3827004-B1 | 4-(1,3,4-OXADIAZOLE-2-YL)PYRIDINE-2(1H)-ONE DERIVATIVES AS HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS FOR THE TREATMENT OF E.G. INFECTIONS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-10-11 | — | — | EP | disclosed |
| CN-116854683-A | Coumarin thiazole derivative and preparation method and application thereof | 中北大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-115745812-A | Preparation method of 2-amino-1- (2,5-dimethoxyphenyl) ethanol | 成都沣德煜晟医药科技有限公司 | 2023-03-07 | — | — | CN | disclosed |
| US-4193804-A | REACTING AN ORGANIC SILVER SALT AND A HALOGEN-RELEASING COMPOUND TO FORM THE SILVER HALIDE WHILE CONTROLLING REDOX POTENTIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1980-03-18 | — | — | US | disclosed |
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3962218-A | NOVEL PROSTANOIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
| US-3955982-A | HYDROCARBONS, HAL | EASTMAN KODAK COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235863-A1 | SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF | TST, NQO1, FNTB | HTT 2068/4885MAPT 940/4885MEN1 3776/4885 |
| US-20040198836-A1 | Process for the synthesis of (+) 2-amino-n-{2, (2,5-dimethoxy phenyl)-2-hydroxyethyl} acetamide monohydrochloride | HACL2, HDHD5, HCN2 | HTT 319/4885MAPT 4356/4885MEN1 3201/4885 |
| US-20090123544-A1 | STIMULUS-RESPONSIVE BIODEGRADABLE POLYMERS AND METHODS OF PREPARATION | PAM, ATF4, MYD88 | HTT 4479/4885MAPT 2463/4885MEN1 2243/4885 |
| US-11958844-B2 | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same | HDAC6, HDAC1, HDAC3 | HTT 265/4885MAPT 1215/4885MEN1 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.